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  • Pagh Shapiro posted an update 5 days, 6 hours ago

    Subclinical hypothyroidism was not associated with depression (OR=0.61, 95% CI 0.20-1.87) nor with the specific depression symptoms. Using lower criteria for subclinical hypothyroidism diagnosis resulted in similar findings.

    In a nationally representative sample of US adults, we observed no association between subclinical hypothyroidism and overall depression risk or any of the individual symptoms of depression.

    In a nationally representative sample of US adults, we observed no association between subclinical hypothyroidism and overall depression risk or any of the individual symptoms of depression.

    Childhood maltreatment and trauma may be risk factors for the development of body dysmorphic disorder (BDD). However, the limited research to date on these topics has been constrained by either the absence of a matched healthy control group or non-comprehensive assessments.

    This study assessed the prevalence and severity of childhood maltreatment and other traumatic events in 52 BDD participants (56% female) and 57 matched controls (51% female) with no history of mental illness, using the Childhood Trauma Questionnaire and a checklist assessing broader traumatic events.

    In comparison with controls, participants with BDD showed a higher prevalence of emotional abuse (61.5% vs. 33.3%) and physical neglect (59.6% vs. 28.1%), as well as more severe overall maltreatment, emotional abuse, and emotional and physical neglect. BDD participants were also more likely to meet cut-offs for multiple types of maltreatment and reported an elevated number and variety of broader traumatic childhood events (e.g., life-threatening illness). In BDD, increasingly severe maltreatment was correlated with greater severity of BDD symptoms, anxiety and suicidal ideation.

    These data suggest that childhood maltreatment and exposure to other traumatic events are common and severe in BDD and are cross-sectionally associated with the severity of clinical symptoms. Adversity linked to maladaptive family functioning during childhood may therefore be especially relevant to people with BDD and could relate to social and emotional processing problems in the disorder.

    These data suggest that childhood maltreatment and exposure to other traumatic events are common and severe in BDD and are cross-sectionally associated with the severity of clinical symptoms. Adversity linked to maladaptive family functioning during childhood may therefore be especially relevant to people with BDD and could relate to social and emotional processing problems in the disorder.

    Self-management support is considered an important task for nurses working in chronic care provision. The complex nature of self-management support makes it necessary to clarify the factors affecting the behaviour of nurses in supporting patients living with chronic illnesses.

    The aim of this review is to synthesize the factors influencing the provision of self-management support as perceived by nurses in the care for patients living with a chronic illness.

    A systematic mixed studies review.

    Studies published in English from 1999 to April 2020 were extracted from five databases CINAHL, PubMed, Cochrane library, EMBASE, and Web of Science.

    The selection process was guided by PICo (Population, phenomenon of Interest, and Context). VX-661 in vitro Studies that highlighted factors associated with the provision of self-management support among nurses, within the context of the top four non-communicable chronic diseases, were included. The risk of bias was carefully assessed. Using data-based convergent synthesis, the ide in self-management of chronic care. Future studies should focus on exploring contextually relevant factors impacting nurses’ supportive role in self-management.

    This review proposed considering a framework of interdependent factors influencing self-management support. It highlighted the need to come up with a comprehensive definition of self-management support that takes into account the emotional aspect as well as patient-as-partner approach. The proposed framework can be useful in tailoring multi-faceted interventions to strengthen nurses’ supportive role in self-management of chronic care. Future studies should focus on exploring contextually relevant factors impacting nurses’ supportive role in self-management.Ammonium (NH4+) and nitrate (NO3-) are the two predominant inorganic nitrogen (N) forms available to crops in agricultural soils. However, little is known about how the NH4+NO3- ratio affect the growth of Brassica napus. Here, we investigated the impact of five NH4+NO3- ratios (1000, 7525, 5050, 2575, 0100) on plant growth, photosynthesis, root morphology, ammonium uptake, nutritional status, oxidative stress response, and relative expression of genes involved in these processes in two rapeseed genotypes with contrasting N use efficiency (NUE). Application of NO3- as a N source extremely improved rapeseed growth compare to NH4+. However, the best growth of the N-inefficient genotype was observed under 7525 NH4+/NO3- ratio, while it happens for the N-efficient genotype only under the sole NO3- environment. The low-NUE genotype exhibited a more developed root system, higher photosynthetic capacity, higher nutrient accumulation, and better NH4+ uptake ability under the 7525 NH4+/NO3- ratio, resulting in a decrease of malondialdehyde (MDA) in root. However, the high-NUE genotype performed better in the above aspects under the NO3–only condition. Nitrate decrease MDA by reducing the activities of superoxide dismutase, peroxidase, and catalase in root of the N-efficient genotype. Moreover, significant differences were detected for the expression levels of genes involved in N uptake and oxidative stress response between the two genotypes under two NH4+/NO3- ratios. Taken together, our results indicate that the N-inefficient rapeseed genotype prefers mixed supply of ammonium and nitrate, whereas the genotype with high NUE prefers sole nitrate environment.Heat stress, resulting from global warming, is considered one of the major challenges to be addressed for increasing plant survival and productivity worldwide. Although plants have a built-in defense mechanism against heat stress, such strategy seems to be insufficient to counteract heat adversities under extreme temperature regimes. Hence, increasing heat tolerance in plants for sustainable yields is one of the biggest challenges for researchers in the coming decades. Conventional plant breeding approach to enhance heat tolerance has gained some successes; however, more efforts are needed to make plants resilient to heat stress for increasing crop production during ongoing climate change. Thus, exploring ‘heat stress mitigation strategies’ using cost-effective and eco-friendly approaches may be quick and sustainable alternatives. The use of silicon (Si) and Si-nanoparticles (Si-NPs) in enhancing heat tolerance in plants has recently gained much attention. Application of Si and Si-NPs can assist plants to overcome heat-induced oxidative stress through the acceleration of reactive oxygen species detoxification by modulating the antioxidant systems and regulating transcription of key genes associated with heat stress responses.

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