Globular glial tauopathy (GGT) is a recently proposed tauopathy characterized by the globular accumulation of four-repeat (4R) tau in the oligodendroglia (globular oligodendroglial inclusion (GOI)) and astrocytes (globular astrocytic inclusion (GAI)), in addition to deposition in neurons. Although it is proposed that GGT should be classified into three different neuropathological subtypes, previous reports have indicated that subclassification might be difficult in some cases. We report an autopy case of a 79-year-old man with behavioral variant frontotemporal dementia (bvFTD). He developed behavioral changes at 67 years of age and had auditory hallucinations and persecutory delusions at admission to a psychiatric hospital at 69 years of age. Neuropathologically, marked atrophy of the frontotemporal lobes and severe degeneration of the white matter and frontopontine tract were observed. The present case corresponded to GGT Type I, as numerous GOIs were observed, predominantly in the frontotemporal region. However, concurrent degeneration of the motor cortex and corticospinal tract suggest characteristics of Type II. Although the relationship between psychotic symptoms and GGT remains unclear, the present case demonstrates heterogeneity of GGT subtypes.

Fruit is generally ripened after harvesting using artificial ripeners such as ethylene, calcium carbide, and ethephon (2-chloroethylphosphonic acid), which can release some residues into the fruits. These residues must be within the maximum levels described in various international standards. The presence of the residues of artificial ripeners must be verified using sensitive and selective detection methods.

The residues of ethephon and vinylphosphonic acid (VPA) were extracted from the pulp of sapota fruit using acetone, and the extract was treated with MgSO

to remove residual water. The extract was subjected to dispersive solid-phase extraction cleanup using DSC-6S sorbent and graphitized carbon black mix, and the cleaned sample was evaporated to dryness and reconstituted in ether containing diazomethane. The analytes were quantitatively identified using gas chromatography/mass spectrometry.

The developed method was observed to be linear in the concentration range of 1-5000 ng/g, and the limits of ds lower than the described maximum residue level of 0-5 μg/g. IBET151 The ethephon residues were below the maximum residue limits in the pulp of sapota fruit ripened with ethephon solutions up to 10 000 mg/L concentration.In the present research, the synthesis, spectroscopic characterization, and structural investigations of a unique ZnII complex of imine-functionalized polyhedral oligomeric silsesquioxane (POSS) is designed, and hereby described, as a catalyst for the synthesis of cyclic carbonates from epoxides and CO2. The uncommon features of the designed catalytic system is the elimination of the need for a high pressure of CO2 and the significant shortening of reaction times commonly associated with such difficult transformations like that of styrene oxide to styrene carbonate. Our studies have shown that imine-POSS is able to chelate metal ions like ZnII to form a unique coordination complex. The silsesquioxane core and the hindrance of the side arms (their steric effect) influence the construction process of the homoleptic Zn4@POSS-1 complex. The compound was characterized in solution by NMR (1H, 13C, 29Si), ESI-MS, UV/Vis spectroscopy and in the solid state by thermogravimetric/differential thermal analysis (TG-DTA), elemental analysis, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS), cross-polarization magic angle spinning (CP MAS) NMR (13C, 29Si) spectroscopy, and X-ray crystallography.

The stable HCNOS isotope compositions can be reported as (a) the isotope ratio of two stable isotopes (R); (b) the isotope delta value (δ); and (c) the atom fraction of the isotopes (x). Recalculations between these different expressions are needed frequently and require the use of the absolute isotope ratio for the zero points of the stable isotope delta scales (R

). The inconsistent use of R

values may lead to a discrepancy in recalculated results.

We summarised the recalculation procedures between different expressions of the stable isotope compositions and introduced a user-friendly EasyIsoCalculator that allows the recalculation between the main expressions of isotope compositions. We mathematically and empirically evaluated the possible inconsistencies in reporting of the stable isotope data due to the use of different R

and different normalisation methods.

The recalculation between δ-values and other expressions of the stable isotope compositions always involves the use of R

. The choice ofepancy arising from the inconsistent use of Rstd. Consistent use of the same Rstd values is required to eliminate the unnecessary discrepancy if different data sets are recalculated from delta value to other expressions.The structural deterioration of archetypical, well-faceted metal-organic frameworks (MOFs) has been evaluated upon exposure to an acidic environment (H2S). Experimental results show that the structural damage highly depends on the nature of the hybrid network (e.g., softness of the metal ions, hydrophilic properties, among others) and the crystallographic orientation of the exposed facets. Microscopy images show that HKUST-1 with well-defined octahedral (111) facets is completely deteriorated, ZIF-8 with preferentially exposed (110) facets exhibits a large external deterioration with the development of holes or cavities in the mesoporous range, whereas UiO-66-NH2 with (111) exposed facets, and PCN-250 with (100) facets does not reflect any sign of surface damage. Despite the selectivity in the external deterioration, X-ray diffraction and gas adsorption measurements confirm that indeed all MOFs suffer an important internal deterioration, these effects being more severe for MOFs based on softer cations (e.g., Cu-based HKUST-1 and Fe-based PCN-250). These structural changes have inevitable important effects in the final adsorption performance for CO2 and CH4 at low and high pressures.