Mixed-factor ANOVAs revealed no main effect of task (F = 1.71, p = 0.196) and group (F = 0.71, p = 0.406) on DTC of gait, while there were significant main effects of both task (F = 23.75, p < 0.001) and group (F = 6.53, p = 0.015) on DTC of cognition. Simple main effects revealed that pwMS had a significantly higher DTC of cognition during BW (+37.6 %, p=0.013), NW (+34.2 %, p=0.014) and NO (+49 %, p=0.016) compared to HA. Additionally, DTC of cognition increased during the more environmentally demanding conditions compared to BW (range +28.4 % to +54.2 %, all p-values<0.01) in both pwMS and HA. Only DTCs of cognition were significantly correlated with PPA and FES-I.

The study findings suggest that CMI may be influenced by the individual/environment at levels above those described by the more mechanistic theories of attention.

The study findings suggest that CMI may be influenced by the individual/environment at levels above those described by the more mechanistic theories of attention.

Falls are a common problem for adults in the United States raising concerns about injuries and the resulting economic burden. As a result, it is critical to develop objective measures to assess dynamic balance and the track progress related to interventions or disease progression over time.

Are there differences in balance between individuals in the community, individuals post-stroke, persons with Multiple Sclerosis (MS), and individuals living with Parkinson’s Disease (PD) as measured with a new instrumented Four Square Step Test (i-FSST)?

The i-FSST was utilized to assess dynamic balance in 41 individuals (11 community dwelling adults and 10 individuals in each group of persons post stroke, with PD, and with MS). Outcome data including the overall duration of the FSST as well unique temporal-spatial stepping patterns through the test, timing of transitions between each quadrant, and the time in each quadrant prior to transitioning.

One-way ANOVAs were conducted to determine whether i-FSST duration, ve data on stability, weight shifting, and weight acceptance that may guide interventions and further assessment.

No study has evaluated the mechanical effect of different magnitudes of long axis-distraction mobilization (LADM) force on hip joint space width (JSW) or the association between the separation of joint surfaces and the strain on hip capsular ligaments.

To compare the joint separation when applying three different magnitudes of LADM forces (low, medium and high) and to analyse the correlation between joint separation, strain on the inferior ilio-femoral ligament and magnitude of applied force.

Repeated measures controlled laboratory cadaveric study.

Three magnitudes of force were applied to 11 cadaveric hip joints (mean age 73 years). Ultrasound images were used to measure joint separation, and strain gauges recorded inferior ilio-femoral ligament strain during each condition.

The magnitude of joint separation was significantly different between low (0.23±0.19mm), medium (0.72±0.22mm) and high (2.62±0.43mm) forces (p<0.001). There were significant associations between magnitude of force, joint separation and the strain on the inferior ilio-femoral ligament during LADM (r>0.723; p<0.001).

Hip joint separation and ligament strain during LADM are associated with the magnitude of the applied force.

Hip joint separation and ligament strain during LADM are associated with the magnitude of the applied force.

In December 2019, the novel coronavirus (SARS-CoV-2) infection was first reported in Wuhan city, central China, which has spread rapidly. The common clinical features of patients with SARS-CoV-2 infection included fever, fatigue, and damage to the respiratory or digestive system. However, it is still unclear whether SARS-CoV-2 infection could cause damage to the central nervous system (CNS) inducing psychiatric symptoms.

Herein, we present the first case of SARS-CoV-2 infection with manic-like symptoms and describe the diagnosis, clinical course, and treatment of the case, focusing on the identifications of SARS-CoV-2 in the specimen of cerebrospinal fluid (CSF). The patient developed manic-like symptoms when his vital signs recovered on illness day 17. After manic-like attack, the detection of SARS-CoV-2 specific IgG antibody in CSF was positive, while the reverse transcriptase-polymerase chain reaction (RT-PCR) on CSF for the SARS-CoV-2 was negative. The patient received Olanzapine for treatment and his mood problems concurrently improved as indicated by scores of Young Manic Rating Scale (YMRS).

This is a single case report only, and the RT-PCR test for SARS-CoV-2 in CSF was not performed simultaneously when SARS-CoV-2 was positive in samples of sputum and stool.

This first case of COVID-19 patient with manic-like symptoms highlights the importance of evaluation of mental health status and may contribute to our understanding of potential risk of CNS impairments by SARS-CoV-2 infection.

This first case of COVID-19 patient with manic-like symptoms highlights the importance of evaluation of mental health status and may contribute to our understanding of potential risk of CNS impairments by SARS-CoV-2 infection.

Depression and hypertension interact through a complex interplay of social, behavioral and biological factors. Despite the huge burden of hypertension in the African sub-region, very little information exists on depression among hypertensive patients. This study assessed the prevalence and factors associated with depression among young and older adult hypertensive patients in Ghana.

Data from the World Health Organization Study on Global AGEing and Adult Health wave 2 (2014/2015) for Ghana was used. selleck chemicals Depression was estimated among participants with blood pressure 140/90mmHg and above. Weighted descriptive statistics and logistic regression with adjusted predictions were carried out. The analysis was performed using Stata 15.

The overall prevalence of depression was 6.3%. Older hypertensive patients had almost twice the prevalence of depression compared with younger patients (8.4% vs 4.5%). The factors which predicted depression among hypertensive patients were educational level, marital status, religion, region of residence, work status, self-rated health (SRH), and unhealthy lifestyle.