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Hassing Burke posted an update 3 weeks, 5 days ago
This study showed that there is statistically significant spinal dysfunction caused due to lymphedema in breast cancer survivors.
The household smoking ban is one potential strategy for reducing exposure to second-hand smoke at home. There is little information about whether concurrent alcohol and tobacco use are related to a smoking ban at home. This study aimed to examine the association between concurrent alcohol and tobacco use with the household smoking ban strategy as reported by the parents of schoolchildren.
We used data from a cross-sectional study that surveyed schoolchildren at 9 schools (grades 6 to 8). A self-administered questionnaire was sent out to the parents of 1,335 schoolchildren. Household smoking ban status was reported by the parents. We used multiple logistics regression to investigate the association between the household smoking ban and alcohol and tobacco use adjusted for potential confounders.
The prevalence of a no-smoking ban in households was 51% (95% confidence interval 48.4%, 53.8%). After adjusting for the number of smokers in a home and perceptions about the harm of exposure to second-hand smoke, the multiple logistics regression results showed that concurrent alcohol and tobacco use in the households (OR = 2.31; 95% CI 1.66, 3.20) had a higher risk of a no-smoking ban.
Our findings showed that concurrent alcohol and tobacco use was associated with a smoking ban status in households. A no-alcohol-drinking-at-home campaign should be adopted and promoted for increasing the rate of smoke-free homes.<br />.
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To investigate the impact of herbal therapy on the quality of life (QoL) among cancer patients and to evaluate the relationship of QoL with age, gender, cancer stage, cancer type, and history of conventional treatment.
A prospective study was targeted on cancer patients receiving herbal therapy from a Traditional and Complementary Medicine (T&CM) clinic in a public hospital from 1st January 2016 to 31st August 2018. Favipiravir clinical trial The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTCQLQ-C30) was distributed to the patients prior to herbal therapy (baseline) and after the sixth and twelfth week of herbal therapy. Socio-demographic and clinical data were collected and analyzed using SPSS version 16.
The majority of the patients were females (60.0%) and were from the Chinese ethnic group (77.4%) with a mean age of 58.72 ± 12.17 years. Approximately 42.4% of patients were in advanced cancer stages at the time of study and 60.7% of patients had undergone radiotherapy before receiving herbal therapy. The most commonly prescribed herbs were Bai Hua She She Cao (90.6%) and Zhen Ren Huo Ming Yin (57.6%). Significant differences in mean score were observed in global health status, overall functional scales, and symptom scales after the sixth and twelfth week of receiving herbal therapy. QoL in terms of global health status and overall functional scales improved with higher scores while symptom scales recorded a lower score after twelve weeks of receiving herbal therapy in the T&CM clinic. Herbal therapy has a significant effect (p < 0.05) on the improvement of QoL of cancer patients. However, gender, cancer stage, cancer type, age, history of radiotherapy, and history of chemotherapy has no effect (p > 0.05).
Herbal therapy did improve the QoL of cancer patients in the southern region of Peninsular Malaysia.
Herbal therapy did improve the QoL of cancer patients in the southern region of Peninsular Malaysia.
Tobacco is one of the main reasons behind the occurrence of oral cancer. Oral cancer, even though being the tenth most common cancer in the world, gets diagnosed at an advanced stage and ends up with poor prognosis. So early diagnosis is the need of the hour. Our study aimed to evaluate the genotoxic changes in patients with different tobacco habits using buccal exfoliated cells.
Buccal smears were taken from smokers (30), smokeless tobacco users (30), combined tobacco users (30) and controls (30) with clinically normal oral mucosa. All the smears were stained with Papanicolaou stain and Feulgen stain and viewed under light microscope for the evaluation of mean number of micronuclei, mean micronuclei per cell, frequency of cells showing micronuclei, nuclear area, cytoplasmic area, nuclear-cytoplasmic ratio.
Mean number of micronuclei, mean micronuclei per cell, frequency of cells showing micronuclei, and nuclear area were significantly increased in tobacco users than controls, especially in combined tobacco users. Nuclear-cytoplasmic ratio was increased and cytoplasmic area was decreased in tobacco users than controls.
Tobacco in any consumable form is genotoxic. Smoking and smokeless tobacco, when consumed together, synergistically causes higher genetic damage. Different tobacco habits have different deleterious effects on oral mucosa, and these effects are more pronounced when the patients have combined habits. So, detecting the genotoxic changes through exfoliative cytology can be used as a simple yet reliable marker for early detection of carcinogenesis.<br />.
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Nationwide epidemiological surveys of behavioral factors and human papillomavirus (HPV) infection among Japanese women are scarce. This study aimed to determine the prevalence, genotype distribution, and significant predictive factors of HPV infection using self-collected vaginal samples from Japanese female people.
The study population consisted of 1,050 female subjects aged 16-75 years (median 30 years). The participants were asked to provide self-collected samples from the vaginal wall using cotton swabs for genotyping of HPV. We compared the participants’ characteristics and detected HPV genotypes to determine significant predictors of HPV infection.
After excluding 47 participants (34 participants of unknown age, 11 virgin participants, 1 participant who engaged in sex with another woman, and 1 participant who did not undergo β-globin detection), 1,003 participants were included in the analysis. Of the 1,003 participants, 426 (42.5%) participants had at least one HPV genotype, 282 (28.1%) participants had high-risk HPV genotypes, 306 (30.