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Lykkegaard Hensley posted an update 3 weeks, 2 days ago
than severe patients. However, at the first follow-up, most patients still had residual pulmonary lesions, which were primarily ground-glass opacity and fibrous strip shadow. The proportion of residual pulmonary lesions was higher in severe cases of COVID-19, which required further follow-up.
Emphysema and chronic obstructive lung disease were previously identified as major risk factors for severe disease progression in COVID-19. Computed tomography (CT)-based lung-density analysis offers a fast, reliable, and quantitative assessment of lung density. Therefore, we aimed to assess the benefit of CT-based lung density measurements to predict possible severe disease progression in COVID-19.
Thirty COVID-19-positive patients were included in this retrospective study. Lung density was quantified based on routinely acquired chest CTs. Presence of COVID-19 was confirmed by reverse transcription polymerase chain reaction (RT-PCR). Wilcoxon test was used to compare two groups of patients. A multivariate regression analysis, adjusted for age and sex, was employed to model the relative increase of risk for severe disease, depending on the measured densities.
Intensive care unit (ICU) patients or patients requiring mechanical ventilation showed a lower proportion of medium- and low-density lung volume cthus suggest that high-density lung tissue could serve as a possible predictor of severe COVID-19.
The aim of this study was to investigate the impact of the primary location of colorectal adenocarcinoma on the lobar distribution of its hepatic metastases based on the streamline hypothesis.
The hospital database was utilised to identify the colorectal cancer patients. Eighty-six patients diagnosed with colorectal adenocarcinoma, who had hepatic metastases on the initial diagnostic stage or on the follow-up investigations, were enrolled the study. Computed tomography (CT) images of the study population were reviewed for the primary location of the colorectal tumour, and the side and number of hepatic metastases.
A total of 481 metastases were counted on CT from 22 right-sided and 64 left-sided colon tumours. The ratio of right-to-left hemiliver involvement was 1.97 1 for whole study population. The right-to-left ratio was calculated as 1.55 1 for right colon tumours and 2.17 1 for left colon tumours (
= 0.106). In the subgroup analysis with unilobar metastatic patients, again there was no significant difference in terms of the colorectal tumours’ primary location (
= 0.325).
The lobar distribution of hepatic metastases from colorectal adenocarcinoma may not be associated with the primary tumour localisation.
The lobar distribution of hepatic metastases from colorectal adenocarcinoma may not be associated with the primary tumour localisation.
To explore whether radiomic features of fluorine-18-fluorodeoxyglucose (
F-FDG) positron emission tomo-graphy-computed tomography (PET/CT) has association with bone marrow infiltration (BMI) in comparison to other conventional PET metrics.
Forty-four patients (with pathologically proven lymphoma disease) underwent staging
F-FDG PET/CT scan. Primary tumour was semi-automatically or manually segmented with a threshold standardised uptake value (SUV) of 3. A total of 73 features were extracted from eight different textures. Spearman correlation was used to test the correlation of features with conventional quantitative metrics such as SUV, metabolic tumour volume, and total lesion glycolysis. Specificity and sensitivity (including 95% confidence intervals [CI]) for each of the studied parameters were derived using receiver operative characteristic (ROC) curves. Univariate and multivariate analyses were used to identify independent predictors associated with BMI.
Correlation between conventional PET metrdiagnosed with lymphoma using
F-FDG PET/CT. Further assessment of long-run emphasis is highly warranted.
18F-FDG PET/CT radiomic features are synergistic to visual assessment of BMI in patients diagnosed with lymphoma using 18F-FDG PET/CT. Further assessment of long-run emphasis is highly warranted.
The purpose of this study was to prospectively assess the Eustachian tube (ET) cartilage using 3 Tesla (3T) magnetic resonance imaging (MRI) and compare the results between healthy ears and those with a middle ear disease.
The study included 56 ears with a middle ear disease as the patient group and 100 ears without a middle ear disease as the control group. The patients’ age ranged from 18 to 65 years. The axial three-dimensional (3D) multiple echo recombined gradient echo (MERGE) sequence and oblique parasagittal planes were obtained. Visualisation of the ET cartilage was assessed on the MR images using a three-point numerical rating score. In the axial plane, the ET lumen’s diameter was measured from the mid-portion of the cartilage.
There was no significant difference between the patient group and the control group according to patients’ age and gender, and the medial laminal thickness of the ET cartilage. In the patient group, the diameter of the ET cartilage was significantly smaller than in the control group. The ET lumen diameter was significantly lower according to each of the three scoring systems.
3T MRI provides an evaluation of the ET cartilage and isthmus level, which are small but important anatomical localisations and surgical landmarks. MR imaging has the potential to provide essential information on ET prior to new surgical treatments, such as balloon dilation for middle ear diseases.
3T MRI provides an evaluation of the ET cartilage and isthmus level, which are small but important anatomical localisations and surgical landmarks. MR imaging has the potential to provide essential information on ET prior to new surgical treatments, such as balloon dilation for middle ear diseases.
The objective of this study was to evaluate the thickness and stiffness of the diaphragm, using ultrasound (US) and strain elastography (SE) in patients with hyperkyphosis due to osteoporotic vertebral fracture.
This prospective and case-control study was conducted between October 2019 and December 2019. Diaphragm thickness, SE, and strain ratio values of patients with hyperkyphosis due to osteoporotic vertebral fracture were compared with those of the control group.
There were 42 patients (14 males, 28 females) with a mean age of 81.10 ± 6.3 years in the kyphosis group and 36 subjects (11 males, 25 females) with a mean age of 81.00 ± 5.5 years in the control group. End-inspirium thickness, change level, and thickening ratio of the diaphragm were significantly higher in the control group (
< 0.001 for all). Strain ratio values were significantly higher in the kyphosis group, and the rate of hardest colour code was significantly higher in the control group. CRT-0105446 molecular weight The diaphragm thickness at end-inspirium and thickening ratio values correlated positively with the forced expiratory volume in the first second (FEV
, %) and forced vital capacity (FVC, %) values.