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    lization is feasible with an excellent safety profile in this patient population and appears to result in improved hepatocellular carcinoma treatment response. © RSNA, 2020.Background Thrombus enhancement (TE) in large vessel occlusion in patients with acute ischemic stroke can be visualized with thin-slab maximum intensity projection (TS-MIP) image reconstruction of CT angiograms. Purpose To evaluate whether TE on TS-MIP reconstructed CT angiograms can be used to predict thrombus composition and stroke source. Materials and Methods This retrospective study included consecutive patients with acute ischemic stroke who underwent thrombectomy in the anterior circulation between August 2016 and July 2019. Stroke types were classified according to the Trial of ORG 10172 in Acute Stroke Treatment. TE on TS-MIP reconstructed CT angiograms was evaluated by two readers. Various clinical and interventional parameters and histopathologic thrombi examination results were compared between the TE-positive and TE-negative groups. The associations between TE and thrombus compositions and stroke sources were analyzed by using multivariable linear and logistic regression models. Results A total oer fibrin-to-platelet fraction and a lower erythrocyte proportion. 1400W price © RSNA, 2020 Online supplemental material is available for this article. See also the editorial by Kansagra and Goyal in this issue.Background The correlation between visual emphysema patterns and subsequent progression of disease may provide a way to enrich a study population for treatment trials of emphysema. Purpose To evaluate the potential relationship between emphysema visual subtypes and progression of emphysema and gas trapping. Materials and Methods Current and former smokers with and without chronic obstructive pulmonary disease (COPD) enrolled in the prospective Genetic Epidemiology of COPD (COPDGene) study (ClinicalTrials.gov identifier NCT02445183) between 2008 and 2011 had their Fleischner Society visual CT scores assessed at baseline, quantitative inspiratory, and expiratory CT and at 5 years. They also underwent pulmonary function testing at baseline CT and at 5 years. The dependent variables were inspiratory lung density at 15th percentile (adjusted for lung volume) as a measure of emphysema and percentage of lung volume with attenuation less than -856 HU at expiratory CT as a measure of air trapping. Statistical analysisression of emphysema in participants who are current or former cigarette smokers with and without chronic obstructive pulmonary disease. © RSNA, 2020 Online supplemental material is available for this article.Background The association of pulmonary embolism (PE) with deep vein thrombosis (DVT) in patients with coronavirus disease 2019 (COVID-19) remains unclear, and the diagnostic accuracy of D-dimer tests for PE is unknown. Purpose To conduct meta-analysis of the study-level incidence of PE and DVT and to evaluate the diagnostic accuracy of D-dimer tests for PE from multicenter individual patient data. Materials and Methods A systematic literature search identified studies evaluating the incidence of PE or DVT in patients with COVID-19 from January 1, 2020, to June 15, 2020. These outcomes were pooled using a random-effects model and were further evaluated using metaregression analysis. The diagnostic accuracy of D-dimer tests for PE was estimated on the basis of individual patient data using the summary receiver operating characteristic curve. Results Twenty-seven studies with 3342 patients with COVID-19 were included in the analysis. The pooled incidence rates of PE and DVT were 16.5% (95% CI 11.6, 22.9; I2 = 0in this issue.We explored associations of elite athletes’ multi-year efficiency of practice and improvement of performance with their current and earlier participation patterns. Participants were 80 adult German track-and-field national-squad athletes. Performance improvement was measured as development of athletes’ highest track-and-field championship level and placing from 19 to 25 years (t1-t2). Practice efficiency was defined as performance improvement per amount of coach-led athletics practice from t1 to t2. Participation variables included amounts of coach-led practice and peer-led play in athletics and other sports through t1 and t1-t2. Analyses involved an advanced machine learning procedure, XGBoost, allowing non-linear, multivariate exploration. We computed two models, one for performance improvement (“good” discriminative performance, AUC = 0.82) and one for practice efficiency (“fair”, AUC = 0.73). Four central findings emerged 1. Childhood/adolescent coach-led multi-sport practice was a critical discriminator of adult practice efficiency and performance improvement. 2. Associations were non-linear, displaying a saturation pattern. 3. The likelihood of achieving high adult practice efficiency was greatest when combining ~1,000-2,500 track-and-field practice hours until t1 with ~1,250 other-sports practice hours until t1. 4. Peer-led engagement in any sport had negligible effects. Childhood/adolescent multi-sport coach-led practice apparently facilitated long-term sustainability of athletes’ development of adult practice efficiency and performance improvement in athletics.Our study examined factors associated with transphobia with a particular focus on the interrelations between religious fundamentalism and contact to impact transphobia. We used an online sample of U.S. adults (Mean age = 38.91 years, SD = 12.58 years; n = 400) to conduct a partially latent variable SEM analysis and tested the direct effects of religious fundamentalism, contact, and gender on transphobia and the indirect effects of religious fundamentalism on transphobia through contact. We additionally tested for gender differences in the structural relations of the variables through a multi-group analysis. Results showed a statistically significant effect of religious fundamentalism, contact, and gender on transphobia. Religious fundamentalism also had a statistically significant indirect effect on transphobia through contact. Gender differences were also found for the effects of religious fundamentalism on contact and on transphobia. We conclude with implications for research and practice.

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