ontinued use of both partial and radical surgical resections to treat duodenal malignancy.Antibiotic resistance is a global problem, searching for new antimicrobial agents is an urgent need. In this study, in vitro antibacterial and antimicrobial effects of milk-derived antimicrobial agents, lactoferrin-derived peptides, lactoferricin (Lfc) and lactoferrampin (Lfa) (alone or in combination) and their association with natural extracts have been explored. The assessment of antimicrobial activity was based on two measurements Minimum Inhibitory Concentration and Fractional Inhibitory Concentration indexes. Lfc alone is more suitable for inhibiting Staphylococcus intermedius and Malassezia pachydermatis, while Lfa against Candida albicans, a synergistic effect of the two peptides against all the three pathogens has been detected. A strong synergy of all the natural extracts with Lfc and Lfa solution against selected microorganisms in vitro was pointed out. Our results suggest that natural-derived compounds, such as milk peptides and vegetal extracts could be promising tools to treat moderate fungal and bacterial infections.Integrity officers working in academic and research settings can be termed “watchdogs” based on characteristics and behaviors that align with their role alert, loyal to their training, responders, notifiers. These watchdogs have a difficult role that involves being the receiver and transmitter of sensitive information that often relates to personal and corporate image, as well as funding. Academic and research organizations must operationalize their mission and vision with more than static policies and procedures about integrity and professionalism, or they risk their watchdogs being reduced to “lap dogs” with a diminutive and submissive presence who are merely loyal to the comfort zone of their employer. A lap dog role has several potential side effects including moral distress and moral injury for the integrity officer, as well as poor service quality for whistle-blowers and other service users. Naphazoline cell line Organizations have a duty to ensure their integrity programs are meaningfully supported, including respecting the human constructs of the watchdog role.For much of the twentieth century, plant physiologists considered themselves in an ideal position to study and explain the functions and processes of plants. Much of that authority stemmed from plant physiologists’ long-standing commitment to experimental control and the integration of the physical sciences into biological practice. This article places plant physiology back in the center of the story of the recent life sciences. It shows the development of parallel experimental research programs into environmental as well as genetic effects on growth and development in plant physiology and genetics, and notes that the pursuit of an experimental environment was celebrated as much as (and occasionally more than) a molecular vision of life throughout most of the twentieth century by much of the plant science community. Thus, this article concludes that the history of the recent life sciences needs new complementary narratives of plant physiology with genetics, new concepts with technological tools, and plant-sized scales with the molecular. The history of the ‘Age of Biology,’ as the plant scientists saw it, helps confront the issue first posed by Evelyn Fox Keller, namely that the history of genetics has overshadowed a larger history of experimental life science. My answer here is through a larger narrative of the rise of the complementary experimental sciences of genes and environments in the life sciences.This study aims to assess the chemical compositions of the essential oils from three Horsfieldia species namely H. fulva Warb., H. sucosa Warb. and H. superba Warb., which are found in Malaysia. The essential oils were derived from the samples through hydrodistillation which were then characterised by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Based on the findings, the H. fulva, H. sucosa and H. superba essential oils represented 98.2%, 98.7% and 98.5% of the total oils, respectively. The major component of H. fulva oil was identified to be germacrene D (20.8%), H. sucosa oil mainly contained α-cadinol (17.5%), whereas H. superba oil was rich in δ-cadinene (18.2%). To the best of our knowledge, this is the first study of the composition of the essential oils from these selected Horsfieldia species.

Operative interventions for breast cancer are generally classified as clean surgeries. Surgical site infections (SSIs), while rare, do occur. This study sought to identify risk factors for SSI, using the National Surgical Quality Improvement Program (NSQIP).

NSQIP’s participant use data files (PUF) between 2012 and 2015 were examined. Female patients with invasive breast cancer who underwent surgery were identified through CPT and ICD9 codes. Non-SSI and SSI groups were compared and the statistical differences were addressed through propensity score weighting. Multivariate logistic regression testing was used to identify predictors of SSI.

This study examined 30 544 lumpectomies and 23 494 mastectomies. SSI rate was 1126/54 038 patients (2.1%). In the weighted dataset, mastectomy, diabetes, smoking, COPD, ASA class-severe, BMI >35 kg/m

, and length of stay (LOS) >1 day were associated with an increased odds ratio (OR) of SSI. The OR for SSI was highest after mastectomy with reconstruction (OR 2.626,

< .001; 95% CI 2.073-3.325). Postoperative variables associated with an increased OR of SSIs included systemic infection, unplanned reoperation wound dehiscence, and renal failure.

Mastectomy, diabetes, smoking, COPD, ASA class-severe, BMI >35 kg/m

, length of stay (LOS) >1 day are associated with an increased OR for SSIs following breast surgery.

1 day are associated with an increased OR for SSIs following breast surgery.

Operating room (OR) inefficiency drives up cost, decreases revenue, and leads to surgeon, staff, and patient dissatisfaction. Given a low mean first-case start rate in our tertiary academic medical center, we developed a process to improve first-case start rates in an effort to increase OR efficiency.

A working group of the OR Executive Committee was constituted to develop and implement a multistep operational plan. This plan was predicated on a sensible staggered start framework, coordination of stakeholder responsibilities, a visual preoperative

checklist tool, real-time measurement, and feedback.

Within 11 days of implementation, 95% of first-start OR cases were tracked to start on time. Throughout the observation period (May 2015-July 2016), the goal of a daily mean 80% on-time start rate was either met or exceeded.

Implementation of an organized collaborative effort led to dramatic improvements in first OR case on-time rates. Such improvement in OR utilization may lead to an increase in staff and patient satisfaction and cost reduction.