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  • Siegel Magnusson posted an update 3 weeks, 1 day ago

    AIM Fetal bowel dilatation (FBD) in the late trimester of pregnancy can be related with varies of prognosis. Our aims were to obtain antenatal factors that might have relevance for the distinct prognosis with FBD. METHODS Seven features of 68 pregnancies presented with FBD were assessed. The best cut-off value to predict intestinal outcomes was selected using receiver-operating characteristics curves, and the effective variables were included into a logistic regression model. RESULTS The best cut-off valves to predict intestinal pathologies were 14.5 mm of fetus dilated loop and 37.7 weeks of gestational age at delivery, respectively. The congenital gastrointestinal tract anomalies included 24 cases (92.3%) of intestine atresia, 1 case (3.85%) of small intestine volvulus and 1 case (3.85%) of midgut malrotation. CONCLUSION Fetal dilated loops and gestational age at delivery are both an independent risk factor for predicting intestinal pathologies of newborns, which should arouse high attention. © 2020 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).Autism spectrum disorder (ASD) is currently viewed as a disorder of cortical systems connectivity, with a heavy emphasis being on the structural integrity of white matter tracts. However, the majority of the literature to date has focused on children with ASD. Understanding the integrity of white matter tracts in adults may help reveal the nature of ASD pathology in adulthood and the potential contributors to cognitive impairment. This study examined white matter water diffusion using diffusion tensor imaging in relation to neuropsychological measures of cognition in a sample of 45 adults with ASD compared to 20 age, gender, and full-scale-IQ-matched healthy volunteers. Tract-based spatial statistics were used to assess differences in diffusion along white matter tracts between groups using permutation testing. The following neuropsychological measures of cognition were assessed processing speed, attention vigilance, working memory, verbal learning, visual learning, reasoning and problem solving, and social cnism. © 2020 International Society for Autism Research, Wiley Periodicals, Inc.Designing and developing advanced electrode materials for high-performance rechargeable batteries have been subjected to extensive studies. Very recently, two-dimensional (2D) nanomaterials have become promising candidates for batteries due to their unique physicochemical properties. In particular, MXenes and phosphorene that exhibit tailored electrical conductivity and ion storage capability have attracted increasing atentions. In this review, we present a comprehensive summary of recent advances of 2D MXenes and phosphorene as electrode materials for high-performance batteries. Their physicochemical properties that include structural configurations and electronic properties of MXenes, and direct bandgap and anisotropic properties of phosphorene are firstly discussed. Then, synthesis methods of the two materials are introduced. Following this, their applications as electrode materials in batteries including lithium-ion batteries (LIBs), sodium-ion batteries (SIBs), potassium-ion batteries (PIBs), lithium-sulfur (Li-S) batteries and metal-air batteries are summarized and discussed in details. An emphasis is placed on analyzing performance enhancement mechanisms to to elucidate fundamental understanding. Finally, challenges and opportunities ahead for MXenes and phosphorene as electrode materials for batteries are featured. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.BACKGROUND There is a need for noninvasive methods for the diagnosis and monitoring of portal hypertension (PH). PURPOSE To 1) assess the correlation of liver and spleen T1 and T1ρ measurements with portal pressures in patients with chronic liver disease, and 2) to compare the diagnostic performance of the relaxation parameters with radiological assessment of PH. STUDY TYPE Prospective. SUBJECTS Twenty-five patients (M/F 16/9, mean age 56 years, range 21-78 years) undergoing portal pressure (hepatic venous pressure gradient [HVPG]) measurements. FIELD STRENGTH/SEQUENCE 1.5T abdominal MRI scan, including T1ρ and T1 mapping. ASSESSMENT Liver and spleen T1ρ and T1 , radiological PH score, and (normalized) spleen length were evaluated. STATISTICAL TESTS Spearman correlation of all MRI parameters with HVPG was assessed. The diagnostic performance of the assessed parameters for prediction of PH (HVPG ≥5 mmHg) and clinically significant PH (CSPH, HVPG ≥10 mmHg) was determined by receiver operating characteristic (RO1 Technical Efficacy Stage 2 J. Magn. Reson. Imaging 2019. © 2020 International Society for Magnetic Resonance in Medicine.BACKGROUND Conventional T2 *-weighted functional magnetic resonance imaging (fMRI) is performed with echo-planar imaging (EPI) sequences that create substantial acoustic noise. The loud acoustic noise not only affects the activation of the auditory cortex, but may also interfere with resting state and task fMRI experiments. PURPOSE To demonstrate the feasibility of a novel, quiet, T2 *, whole-brain blood oxygenation level-dependent (BOLD)-fMRI method, termed Looping Star, compared to conventional multislice gradient-echo EPI. STUDY TYPE Prospective. PHANTOM/SUBJECTS Glover stability QA phantom; 10 healthy volunteers. FIELD STRENGTH/SEQUENCE 3.0T gradient echo (GE)-EPI and T2 * Looping Star fMRI. ASSESSMENT Looping Star fMRI was presented and compared to GE-EPI with a working memory (WM) task and resting state (RS) experiments. Temporal stability and acoustic measurements were obtained for both methods. Functional maps and activation accuracy were compared to evaluate the performance of the novel sequence. STAh only 0.5 dB above ambient noise. From the comparison with GE-EPI, further developments of Looping Star fMRI should target increased sensitivity and spatial specificity for both RS and task experiments. LEVEL OF EVIDENCE 2. TECHNICAL EFFICACY STAGE 1. © 2020 The Authors. Journal of Magnetic Resonance Imaging published by Wiley Periodicals, Inc. AS-703026 research buy on behalf of International Society for Magnetic Resonance in Medicine.

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