We review fiber-based multimode interference (MMI) devices with a particular focus on optical fiber-based sensing applications. The present review complements a recently published, extensive review where the sensing of conventional physical variables such as refractive index, temperature, displacement, and strain was covered. This review focuses on MMI fiber sensors for nonconventional physical variables, including mechanical, electromagnetic, chemical, and optical, covering around fifteen years of work in the field. Finally, by the end of this paper, we also review some new trends of MMI-based schemes based on polymer fibers, for wavelength-locking applications, for retrieving the thermo-optic coefficient of liquid samples, and for measuring the dynamics of complex fluids.Enterococcus faecalis is a Gram-positive pathogen which colonizes human intestinal surfaces, forming biofilms, and demonstrates a high resistance to many antibiotics. Especially, antibiotics are less effective for eradicating biofilms and better alternatives are needed. In this study, we have isolated and characterized a bacteriophage, PBEF129, infecting E. faecalis. PBEF129 infected a variety of strains of E. faecalis, including those exhibiting antibiotic resistance. Its genome is a linear double-stranded DNA, 144,230 base pairs in length. AGS 200 Its GC content is 35.9%. The closest genomic DNA sequence was found in Enterococcus phage vB_EfaM_Ef2.3, with a sequence identity of 99.06% over 95% query coverage. Furthermore, 75 open reading frames (ORFs) were functionally annotated and five tRNA-encoding genes were found. ORF 6 was annotated as a phage endolysin having an L-acetylmuramoyl-l-alanine amidase activity. We purified the enzyme as a recombinant protein and confirmed its enzymatic activity. The endolysin’s host range was observed to be wider than its parent phage PBEF129. When applied to bacterial biofilm on the surface of in vitro cultured human intestinal cells, it demonstrated a removal efficacy of the same degree as cefotaxime, but much lower than its parent bacteriophage.The Internet of Things (IoT) has emerged from the proliferation of mobile devices and objects connected, resulting in the acquisition of periodic event flows from different devices and sensors. However, such sensors and devices can be faulty or affected by failures, have poor calibration, and produce inaccurate data and uncertain event flows in IoT applications. A prominent technique for analyzing event flows is Complex Event Processing (CEP). Uncertainty in CEP is usually observed in primitive events (i.e., sensor readings) and rules that derive complex events (i.e., high-level situations). In this paper, we investigate the identification and treatment of uncertainty in CEP-based IoT applications. We propose the DST-CEP, an approach that uses the Dempster-Shafer Theory to treat uncertainties. By using this theory, our solution can combine unreliable sensor data in conflicting situations and detect correct results. DST-CEP has an architectural model for treating uncertainty in events and its propagation to processing rules. We describe a case study using the proposed approach in a multi-sensor fire outbreak detection system. We submit our solution to experiments with a real sensor dataset, and evaluate it using well-known performance metrics. The solution achieves promising results regarding Accuracy, Precision, Recall, F-measure, and ROC Curve, even when combining conflicting sensor readings. DST-CEP demonstrated to be suitable and flexible to deal with uncertainty.For centuries, scientists have been intrigued by the origin of dioecy in plants, characterizing sex-specific development, uncovering cytological differences between the sexes, and developing theoretical models. Through the invention and continued improvements in genomic technologies, we have truly begun to unlock the genetic basis of dioecy in many species. Here we broadly review the advances in research on dioecy and sex chromosomes. We start by first discussing the early works that built the foundation for current studies and the advances in genome sequencing that have facilitated more-recent findings. We next discuss the analyses of sex chromosomes and sex-determination genes uncovered by genome sequencing. We synthesize these results to find some patterns are emerging, such as the role of duplications, the involvement of hormones in sex-determination, and support for the two-locus model for the origin of dioecy. Though across systems, there are also many novel insights into how sex chromosomes evolve, including different sex-determining genes and routes to suppressed recombination. We propose the future of research in plant sex chromosomes should involve interdisciplinary approaches, combining cutting-edge technologies with the classics to unravel the patterns that can be found across the hundreds of independent origins.Although computed tomography (CT) scans are very useful for identification or surveillance of malignancy, they are also associated with the risk of cancer caused by ionizing radiation. We investigated the risk of second primary malignancies (SPMs) after frequent abdominopelvic CT scans in a cohort of Korean patients with early gastric cancer (EGC). We performed a cohort study of 11,072 patients who underwent resection for EGC at Samsung Medical Center and validated the results using data from 7908 patients in a Korean National Health Insurance Service cohort. Cox proportional hazards regression model was used to estimate hazard ratios (HRs) for intra-abdominal SPM. During 43,766.5 person-years of the follow-up at our center, 322 patients developed intra-abdominal SPMs. Patients who underwent receiving >8 abdominopelvic CT scans had a significantly greater risk of developing SPM (HR, 2.73; 95% CI, 1.66-4.50; p less then 0.001) than those who had with ≤8 scans. For each additional abdominopelvic CT scan, the adjusted HR for SPM was 1.09 (95% confidence interval (CI), 1.03-1.14). Similar results were observed in the Korean National Health Insurance Service cohort (adjusted HR, 1.14; 95% CI, 1.07-1.22). Significantly elevated risk of SPM was still observed when considering a 2-year latency period (adjusted HR, 2.43; 95% CI, 1.37-4.48) and a 3-year latency period (adjusted HR, 2.17; 95% CI, 1.06-4.47). Frequent abdominopelvic CT scans are associated with an elevated risk of SPMs after the treatment of EGC. Thus, physicians need to weigh carefully the clinical benefits of CT examinations against the potential risks of radiation exposure.