A miniature millimeter-wave 5G antenna fabricated using anodized aluminum oxide (AAO) is devised and demonstrated for mobile devices. The proposed structure creates a dielectric layer on an aluminum plate using AAO topology and allows the antenna pattern to be placed on the dielectric layer. The proposed AAO-based antenna reduces the size (1.87 (0.18λ0) mm × 2.34 (0.22λ0) mm) of the antenna in proportion to the dielectric constant (εr = 6.7), which is higher than those of the conventional materials such as polycarbonates (PC) or a flame retardant (FR4). In addition, it is possible to precisely control the dielectric layer dimensions and generate a dielectric layer on the metal substrate itself, which greatly increases the design freedom. As a result, the devised antenna resonates at 29 GHz, and the measured gain is 5.02 dBi.Kaolinite nanotube particles (KNTs) were synthesized by a chemical exfoliation and scrolling process in the existence of sonication waves. The KNT product was identified as a mesoporous material (12 nm in pore diameter) with high surface area (105 m2/g) and promising adsorption affinity for the levofloxacin antibiotic (LVOX) residuals in wastewater. The KNT particles were used as a fixed bed in the continuous adsorption column system for LVOX considering the essential variables. The investigation of the KNT fixed bed in a continuous column for 1800 min verified its suitability to reduce the LVOX content in 9 L of polluted solutions by 80.4%. This was recognized after using the KNT bed of 4 cm in height, a flow rate of 5 mL/min, a pH value of 8, a total flow interval of 1800 min, and an LVOX concentration of 10 mg/L. The regeneration study of the bed declared effective recyclability properties for the KNT particles in the LVOX adsorption column system. The dynamic properties of the KNT bed-based column system were explained based on Thomas, Adams-Bohart, and the Yoon-Nelson kinetic models. The LVOX adsorption reaction by KNTs follows Langmuir behavior with homogeneous and monolayer uptake form. The Gaussian energy (2.05 kJ/mol) and the thermodynamic parameters emphasized physical, spontaneous, and exothermic adsorption reactions for LVOX by KNTs.A new strategy for designing and assembling a novel class of functionalized pyridine-based benzothiazole and benzimidazole incorporating sulfonamide moieties was developed. The synthesis was carried out by reacting N-cyanoacetoarylsulfonylhydrazide with various electrophiles such as 2-(benzo[d]thiazol-2-yl)-3,3-bis(alkylthio)acrylonitriles and 2-(benzo[d]imidazol-2-yl)-3,3-bis(methylthio)-acrylonitriles, as well as 2-ethoxyl acrylonitrile derivatives. The synthesized compounds were tested for their antiviral and antimicrobial potency. Two of the synthesized compounds, 15c and 15d, showed more than 50% viral reduction against HSV-1 and CBV4, with significant IC50 and CC50 values. The two potent compounds 15c and 15d have also shown inhibitory activity against Hsp90α protein with IC50 values of 10.24 and 4.48 μg/mL, respectively. A combination of 15c and 15d with acyclovir has led to IC50 values that are lower than that of acyclovir alone. Molecular modeling studies were used to identify the interactions between the 15c and 15d compounds and the active site of Hsp90α enzyme. The antimicrobial investigation of the new compounds has also shown that 8b and 15d exhibited a higher inhibition zone (IZ) than sulfadiazine and gentamicin against Klebsiella pneumonia, whereas 9a showed higher IZ than ampicillin against Staphylococcus aureus. According to the enzyme assay study on dihydrofolate reductase, 9a was shown to be the most potent compound among all examined compounds.A method of prediction of location of water cresting and characterizing its intensity in a horizontal well in a water-drive reservoir is introduced for the first time. A mechanistic model for water cresting derived from Darcy’s equation incorporating the main parameters reported in the literature affecting water cresting-viscosity, well distance to the aquifer, wellbore pressure gradient, and reservoir heterogeneity-is introduced with two new characterizing parameters. First is a model-derived parameter, called the breakthrough coefficient, which is defined as the ratio of the average time of breakthrough to the time of breakthrough for a segment of the well, with the model-predicted location of water cresting corresponding to the well segment with the largest breakthrough coefficient. The second is the Cresting index, which is the ratio of the maximum breakthrough coefficient to the minimum breakthrough coefficient as a characterizing parameter, with a well with a higher cresting index corresponding to a faster breakthrough in a group of similar wells. This methodology was validated through a series of sophisticated experimental corefloods and found to predict 78% of the location of the water cresting accurately. The cresting index is found to be weakly correlated with the speed of breakthrough among similar wells.The instability of an amide bond with dilute trifluoroacetic acid (TFA) is a rare chemical event. The native amide bonds are stable even in the neat TFA, which is one of the reagents that releases the peptides from the solid support in the solid-supported peptide synthesis method. In the repertoire of unnatural peptidomics, α-/β-hydrazino acids and their peptides are explored for the synthesis of N-amino peptide derivatives, and their amide bonds are stable in TFA (∼100%) as natural amide bonds. This report describes the synthesis of a β-hydrazino acid analogue as β-troponylhydrazino acid, containing a nonbenzenoid natural troponyl scaffold. selleck chemicals llc The structural and conformational studies of their hybrid di-/tripeptides with the natural amino acid show that the 2-aminotroponyl residue is involved in hydrogen bonding. Surprisingly, the amide bond of β-troponylhydrazino peptides is cleavable with TFA (∼20%) through the formation of a new heterocyclic molecule N-troponylpyrazolidinone or troponylpyrazolidinone. Tropolone and related compounds are excellent biocompatible chromophores. Hence, β-troponylhydrazino acid could be employed for tuning the peptide structure and considered a promising chromophoric acid-sensitive protecting group of a free amine of amino acids/peptides. It could be applied for the estimation of the free amine group functionality by a UV-vis spectrophotometer.