Allografts were fresh in 4 studies, demineralized in 2 studies, and freeze-dried after sterilization in 1 study. All scores performed in the different studies increased between pre-operative and post-operative evaluations (mean + 36.8 points for the ASES). Global rate of recurrence was 3.9% (11 patients) (0-11%), comprising 6 cases of dislocation (2.1%) and 5 subluxations (1.8%). Allograft healing occurred in 93.5% of cases. Conclusions This systematic review data suggest that allograft reconstructions in anterior glenohumeral instability could be a viable alternative to similar reconstructions with autografts and provide close clinical/radiological outcomes, at short and mid-term follow-up. Prospective randomized studies are needed to confirm these results.Background With the novel coronavirus-induced disease (COVID-19), there is the fear of nosocomial infections and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissions to healthcare workers (HCW). We report the case of a 64-year-old male patient who underwent explantation of a shoulder prosthesis due to a periprosthetic infection. He was tested SARS-CoV-2 positive 7 days after admission to the orthopaedic department following strict infection control measures, routinely including screening all patients for multi-drug-resistant organism (MDRO) colonization upon admission. Aim of our study is to report on the spreading potential of SARS-CoV-2 in a healthcare setting if standard contact precautions and infection control measures have been established. Methods All HCW with exposure to the patient from day of admission until confirmed diagnosis of COVID-19 were identified and underwent oropharyngeal swab testing for SARS-CoV-2 by real-time RT-PCR. Results Sixty-six HCW were identified nine orthopaedic surgeons, four anaesthesiologists, 25 orthopaedic nurses, five nurse anesthetists, eight scrub nurses, five nursing students, two medical assistants and seven service employees. Fourteen HCW (21%) showed clinical symptoms compatible with a SARS-CoV-2 infection cough (n = 4), sore throat (n = 3), nasal congestion (n = 3), dyspnea (n = 2), fever (n = 1), headache and myalgia (n = 1). SARS-CoV-2 was not detected in any of the 66 HCW. Conclusion Hygienic measures and contact precautions, aimed at preventing the spread of MRDO, may have helped to prevent a SARS-CoV-2 transmission to HCW-despite high-risk exposure during intubation, surgical treatment and general care. Level of evidence IV, case series.Purpose To examine the effects of intermittent hypoxic breathing at rest (IHR) or during exercise (IHT) on blood pressure and nitric oxide metabolites (NOx) and hypoxia-inducible factor-1 alpha levels (HIF-1α) over a 6-week period. Methods 47 hypertensive patients were randomly allocated to three groups hypertensive control (CON n = 17; IHR n = 15 and IHT n = 15. The CON received no intervention; whereas, IH groups received eight events of hypoxia (FIO2 0.14), and normoxia (FIO2 0.21), 24-min hypoxia and 24-min normoxia, for 6 weeks. The baseline data were collected 2 days before the intervention; while, the post-test data were collected at days 2 and 28 after the 6-week intervention. Results We observed a significant decrease of the SBP in both IH groups IHR (- 12.0 ± 8.0 mmHg, p = 0.004 and – 9.9 ± 8.8 mmHg, p = 0.028, mean ± 95% CI) and IHT (- 13.0 ± 7.8 mmHg, p = 0.002 and – 10.0 ± 8.4 mmHg, p = 0.016) at days 2 and 28 post-intervention, respectively. Compared to CON, IHR and IHT had increased of NOx (IHR; 8.5 ± 7.6 μmol/L, p = 0.031 and IHT; 20.0 ± 9.1 μmol/L, p less then 0.001) and HIF-1α (IHR; 170.0 ± 100.0 pg/mL, p = 0.002 and IHT; 340.5 ± 160.0 pg/mL, p less then 0.001). At 2 days post-intervention, NOx and HIF-1α were negatively correlated with SBP in IHT. Conclusion IH programs may act as an alternative therapeutic strategy for hypertension patients probably through elevation of NOx and HIF-1α production.Purpose Intra-limb and muscular coordination during gait are the result of the organisation of the neuromuscular system, which have been widely studied on a flat terrain. Environmental factors, such as the inclination of the terrain, is a challenge for the postural control system to maintain balance. Therefore, we hypothesised that the central nervous system flexibly modifies its control strategies during locomotion on slopes. Methods Ten subjects walked on an inclined treadmill at different slopes (from – 9° to + 9°) and speeds (from 0.56 to 2.22 m s-1). Intra-limb coordination was investigated via the Continuous Relative Phase, whereas muscular coordination was investigated by decomposing the coordinated muscle activation profiles into Basic Activation Patterns. Results A greater stride to stride variability of kinematics was observed during walking on slopes, as compared to walking on the level. On positive slopes, the stride period and width present a greater variability without modification of the time-pattern of the muscular activation and of the variability of intersegmental coordination. On negative slopes, the stride width is larger, the variability of the stride period and of the inter-segmental coordination is greater and the basic activation patterns become broader, especially at slow speeds. Conclusion Our findings suggest that the control strategy of downhill walking corresponds to a more conservative gait pattern, which could be adopted to lower the risk of falling at the cost of a greater energy consumption. In uphill walking, where metabolic demands are high, the strategy adopted may be planned to minimise energy expenditure.Purpose Landing involves a tuned anticipatory control to allow for soft and safe contact with the ground. Fearful situations are known to affect postural control strategies during standing, but it is still unclear how fear interferes with the control of a voluntary dynamic task requiring coordination between posture and movement. Methods Ground reaction forces, limb movements, physiological arousal, and perceived levels of confidence and fear of falling were recorded when hopping off a box to a platform situated 0.8 m above ground and 3.2 m above ground. Results Height induced a perceived threat as arousal was augmented by the elevated surface for all subjects. learn more Threat induced by height modifies the way participants land, leading to a stiffer landing, as evidenced by an increased loading rate at touchdown during high threat conditions. Greater psychological and physiological changes are associated with greater changes in the control of landing individuals that are less confident/more fearful appear to compensate for this stiffer landing, by slowing down their landing.