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  • Lindgaard Morse posted an update 1 day, 6 hours ago

    Alternatives to tourniquets include portal-site epinephrine injections. This prospective, randomised-controlled, double-blinded study compared intraoperative visibility and safety of portal-site injections with tourniquets in arthroscopic meniscectomies.

    Sixty eligible adults [16-55ys, excluding vascular/neuromuscular/systemic illnesses] were randomly/equally divided across 3 groups A (controls)-local portal injections; B-local injections with tourniquet; C-local and 1200,000epinephrine injections. A single surgeon operated blinded to patient group. Intraoperative visibility, surgeon visual analogue score (VAS)and other details were recorded.

    Superior visibility [p=0.003,p=0.027] and VAS [p=0.010,p=0.042] were reported in groups B, C versus A, Visibility [p=0.705; p=0.805] and operating times [p=0.05] were comparable between B and C.

    Portal-site epinephrine injections emerged as tenable surrogates for tourniquets for clear visualization in arthroscopy.

    Portal-site epinephrine injections emerged as tenable surrogates for tourniquets for clear visualization in arthroscopy.

    Computer- and robotic-assisted technologies have recently been introduced into orthopedic surgery to improve accuracy. Each requires intraoperative “bone registration,” but existing methods are time consuming, often inaccurate, and/or require bulky and costly equipment that produces substantial radiation.

    We developed a novel method of bone registration using a compact 3D structured light surface scanner that can scan thousands of points simultaneously without any ionizing radiation.Visible light is projected in a specific pattern onto a 3×3 cm

    area of exposed bone, which deforms the pattern in a way determined by the local bone geometry. A quantitative analysis reconstructs this local geometry and compares it to the preoperative imaging, thereby effecting rapid bone registration.A registration accuracy study using our novel method was conducted on 24 CT-scanned femur Sawbones®. We simulated exposures typically seen during knee/hip arthroplasty and common bone tumor resections. The registration accuracy of our technique was quantified by measuring the discrepancy of known points (i.e., pre-drilled holes) on the bone.

    Our technique demonstrated a registration accuracy of 0.44±0.22mm. This compared favorably with literature-reported values of 0.68±0.14mm (

    -value=0.001) for the paired-point technique

    and 0.86±0.38mm for the intraoperative CT based techniques

    (not enough reported data to calculate

    -value).

    We have developed a novel method of bone registration for computer and robotic-assisted surgery using 3D surface scanning technology that is rapid, compact, and radiation-free. We have demonstrated increased accuracy compared to existing methods (using historical controls).

    We have developed a novel method of bone registration for computer and robotic-assisted surgery using 3D surface scanning technology that is rapid, compact, and radiation-free. We have demonstrated increased accuracy compared to existing methods (using historical controls).

    The whole world is under the effects of the COVID-19 pandemic which has put all nations in a unique lockdown situation to contain the disease. Though the environment got ameliorated with low pollution levels, this unexpected lockdown has taken a toll on humans’ mental health. As the effects of lockdown can affect college students due to fear, anxiety and stress, this study intends to assess the attitude of the university students.

    An online questionnaire survey comprising 15 questions was conducted among four South Indian state university students. Their responses were recorded through Google Forms. The submitted responses were analysed using SPSS software version 17.

    In total, 1241 responses were recorded from university students belonging to various faculties. PDD00017273 in vitro Though 43% considered this lockdown as a convenient break, 60% could not focus on their studies. The importance of renewing relationships was felt by 47%, and 83% tried to learn a new skill. Students from Tamil Nadu were looking forward towards a brighter future after the lockdown.

    This survey conducted in the early days of lockdown indicated that the university students were not anxious about the long-term effects of the pandemic but showed a decline in their academic performance.

    This survey conducted in the early days of lockdown indicated that the university students were not anxious about the long-term effects of the pandemic but showed a decline in their academic performance.The SARS-CoV-2 (COVID-19) pandemic is a worldwide public health emergency with widespread impact on health care delivery. Unforeseen challenges have been noted during administration of usual haematology care in these unusual COVID-19 times. Medical services have been overstretched and frontline health workers have borne the brunt of COVID-19 pandemic. Movement restrictions during lockdown prevented large sections of population from accessing health care, blood banks from holding blood drives, and disrupted delivery of diagnostic hematology services. The disruption in hematology care due to COVID-19 pandemic in India has been disproportionately higher compared to other subspecialities as hematology practice in India remains restricted to major cities. In this review we chronicle the challenges encountered in caring for hematology patients during the COVID-19 pandemic in India and put forth recommendations for minimizing their impact on provision of hematology care with special emphasis on hematology practice in lower and middle income countries (LMICs).Nutritional deficiency is associated with impaired immunity and increased susceptibility to infections. The complex interactions of trace elements with the macromolecules trigger the effective immune response against the viral diseases. The outcome of various viral infections along with susceptibility is affected by trace elements such as zinc, selenium, iron, copper, etc. due to their immuno-modulatory effects. Available electronic databases have been comprehensively searched for articles published with full text available and with the key words “Trace elements”, “COVID-19”, “Viral Infections” and “Immune Response” (i.e. separately Zn, Se, Fe, Cu, Mn, Mo, Cr, Li, Ni, Co) appearing in the title and abstract. On the basis of available articles we have explored the role of trace elements in viral infections with special reference to COVID-19 and their interactions with the immune system. Zinc, selenium and other trace elements are vital to triggerTH1 cells and cytokine-mediated immune response for substantial production of proinflammatory cytokines.

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