s with few choices. This necessitates periodic surveillance of causative organisms and their antibiotic-susceptibility pattern to help in formulating hospital antibiotic policy. The antibiotic stewardship program is yet to be adopted in our hospital.Introduction Severe ischemia induces cerebral excitability imbalance before completion of infarct. To investigate the clinical availability of this imbalance with ischemic monitoring, paired-pulse somatosensory evoked potentials (SEPs) were performed in conjunction with conventional SEPs during carotid endarterectomy. Methods For carotid endarterectomy patients with hemodynamic deficits of the middle cerebral artery area (n = 34), the excitability imbalances (Q) were measured by paired-pulse SEPs, wherein the second response (A2) was divided by the first (A1; Q = A2/A1). Regional cerebral saturation (rSO2) was also measured. Occlusion was performed twice using shunting. Results Each carotid occlusion induced a significant decrease in mean A1 and rSO2, and an increase in mean Q values (p less then 0.001), which returned to the baseline level after occlusion. While neuronal imbalances were mostly transient, persistently increased Q values were observed in four cases (11.8%), all indicating postoperative abnormalities in diffusion-weighted magnetic resonance imaging (100%). Meanwhile, A1 detected the postoperative abnormality in only one case (25%). Preoperative Q values at the time of surgery were significantly higher in symptomatic patients having the upper limb deficits than those without (p less then 0.01), indicating persistent or permanent imbalances. Conclusion Paired-pulse SEPs reliably identified transient, persistent or permanent neuronal imbalances, depending on the ischemic severity. These preliminary results indicated that paired-pulse SEPs, in combination with conventional SEPs (A1), may offer better ischemic monitoring.Introduction Although there have been important developments in microsurgery in recent years, there is no current and comprehensive bibliometric study in the literature. In this study, we aimed to present a summary of the articles published on microsurgery between 1980 and 2019 with bibliometric analysis. Methods Articles published on microsurgery between 1980 and 2019 were withdrawn from the Web of Science database and analyzed by bibliometric methods. Citation analysis was performed to identify effective journals and articles. Keyword cluster and trends analyses were performed for a detailed analysis of the researched topics. Relationships between the article numbers of the countries and gross domestic product (GDP) and human development index (HDI) values were investigated using Spearman’s correlation coefficient. A linear regression analysis was used to estimate the number of articles to be published in the future. Results A total of 3,537 publications related to microsurgery were found. Bibliometric analyses were performed in 2,063 articles (58.3%) of these publications. The most active countries in publishing were the United States (504), Germany (286), and Italy (154), respectively. A statistically significant correlation was found between the article numbers and the GDP and HDI sizes of the countries (r = 0.758, p less then 0.001, r = 0.659, p less then 0.001). Conclusion The economic size and development levels of the countries were an important factor in academic productivity in microsurgery. Undeveloped countries should be encouraged by performing multidisciplinary studies in this regard.Immune checkpoint inhibitors (ICIs) are novel humanized monoclonal antibodies that release the brakes on the immune system, resulting in the destruction of tumor cells. ICIs are approved for a variety of hematological and solid organ malignancies, and the list has been growing since the approval of ipilimumab in 2011. Ceralasertib ICIs are associated with a variety of immune-related adverse events (irAEs). irAEs commonly affect the skin, the gastrointestinal (GI) tract, and the endocrine system. Acute kidney injury (AKI) due to ICIs (ICI-AKI) occurs in a minority of patients, and it is usually due to acute tubulointerstitial nephritis (ATIN). Treatment with corticosteroids is usually successful. There have been reports of electrolyte disorders due to ICIs, including hyponatremia, hypocalcemia, hypokalemia, and Fanconi syndrome. The diagnosis of electrolyte disorders requires vigilance and routine laboratory monitoring.Background The aim of this study was to evaluate the clinical and radiological results of patients with acute type III Rockwood acromioclavicular joint (ACJ) dislocation treated surgically by employing tension band wiring. Methods The study included 24 patients with traumatic type III ACJ dislocations according to the Rockwood classification. The clinical and radiological outcomes of patients were assessed at the final follow-up visit. Implant failure and reduction loss were assessed using radiographs, whereas the Constant-Murley scoring system was used to assess the patients clinically. Results The mean follow-up period was 3.5 ± 1.3 years (range 1-6 years). The mean age of the patients was 41.8 ± 11.7 years (range 19-64 years) and the mean length of hospital stay was 2.3 days (range 1-6 days). The fixation material was removed postoperatively at an average of 7.2 ± 9.9 months (range 3-40 months). At the end of the follow-up period, the mean Constant-Murley score was 72.5 ± 12.8 (range 50-90). The ACJ reduction was stable in 13 (54.2%) patients. Residual subluxation was detected in 11 (45.8%) patients. Distal clavicular osteolysis was noted in six (25%) patients. Acromioclavicular osteoarthritis was detected in five (20.8%) operated shoulders on follow-up radiographs. During the follow-up, Kirschner-wire migration and breakage occurred in four (16.6%) and seven (29.1%) patients, respectively. Conclusions This study showed that surgical treatment with the tension band wiring method provided functionally satisfactory results even if complications developed because of the presence of implants. Independent of age, we can recommend it as the primary treatment method for patients who do not have very high expectations regarding their shoulder function. Additionally, we think that reducing the duration of implant retention will reduce the incidence of complications.