Genes involved in fundamental cellular process played an important role in the genetic architecture of syndromic short stature. Distinct genetic architectures and pathophysiological processes underlie isolated and syndromic short stature.The ongoing COVID-19 pandemic and its unprecedented global societal and economic disruptive impact highlight…[Read more]

The complex mTORC2 is accepted to be the kinase that controls the phosphorylation of the hydrophobic motif, a key regulatory switch for AGC kinases, although whether mTOR directly phosphorylates this motif remains controversial. Here, we identified an mTOR-mediated phosphorylation site that we termed the TOR interaction motif (TIM; F-x3-F-pT),…[Read more]

P < .05 was set as the significance level.

Our hypothesis was that chronic kidney disease is associated with increased atrial fibrosis and a higher risk of arrhythmia recurrence and that restoration of normal rhythm through catheter ablation is associated with improved kidney function.

10.…[Read more]

Polypectomy is a widely used and effective procedure to treat precancerous polyps. Delayed post-polypectomy bleeding (DPPB), a common complication of polypectomy, may diminish the utility of this procedure. Previous data on the efficacy of hemoclips has been conflicting, therefore we aimed to collectively evaluate and analyze the data to reach a…[Read more]

TNBC is the most aggressive and hormone receptor-negative subtype of breast cancer with molecular heterogeneity in bulk tumors hindering effective treatment. Toll-like receptors (TLRs) have the potential to ignite diverse immune responses in the tumor microenvironment (TME). This encouraged us to screen their transcript expression in the…[Read more]

The responses to an open-ended item on the survey provided context to the results and shed light on effective design practices. Several recommendations for best practices in developing etextbooks are identified for educators to consider.Visual display terminal syndrome is a health problem that occurs when an individual looks at a visual display…[Read more]

Directing nanoparticles into ordered organization in polymer matrix to improve macroscopic properties of nanocomposites remains a challenge. Herein, by means of theoretical simulations, we show the high permittivity of hybrid nanostructures designed with mixtures of AB block copolymer-grafted nanoparticles and lamella-forming AC diblock…[Read more]

Directing nanoparticles into ordered organization in polymer matrix to improve macroscopic properties of nanocomposites remains a challenge. Herein, by means of theoretical simulations, we show the high permittivity of hybrid nanostructures designed with mixtures of AB block copolymer-grafted nanoparticles and lamella-forming AC diblock…[Read more]

BAP31 is furthermore implicated in a growing number of cancers and other diseases, and several viruses have been found to target it to promote their survival or life cycle progression. The purpose of this review is to provide an overview and examination of the basic properties, functions, mechanisms, and roles in disease of BAP31.

As a…[Read more]