n the asthma trial were lower than in atopic dermatitis trials and were similar for dupilumab- and placebo-treated patients. Most events were mild to moderate, most recovered/resolved, and none prompted study withdrawal. These results are similar to those reported in adult trials and support a drug-disease interaction. CLINICALTRIALS.…[Read more]

The second color channel is exploited to monitor a small fraction of labeled lipids to determine the total area increase. Here, we use this method to determine the insertion area per molecule of Sar1, a protein of the COPII complex, which is involved in transport vesicle formation. Sar1 has an N-terminal amphipathic helix, which is responsible for…[Read more]

Pregnancy and childbirth are the main causes of pelvic floor dysfunction (PFD). Although pelvic floor muscle tension is typically measured at 42 days postpartum to assess the severity of PFD and provide timely rehabilitation, it is still impossible to predict PFD and take targeted preventive measures in clinical practice. A PFD prediction model…[Read more]

COVID-19 has brought the world to a standstill with a wave of destruction in country after country with tremendous loss of lives and livelihood in advanced to developing nations. Whole world is staring at the prospect of repeated lockdowns with another wave of COVID-19 predicted to hit the world in September of 2020. The second wave is assumed to…[Read more]