While a simpler transition probability model, when tested as a single predictor in the statistical analyses, accounted for significant variance in the data, the goodness-of-fit with the data significantly improved when the language-based complexity measure was included in the statistical model, while the variance explained by the transition…[Read more]

Collectively, our work utilizes flexible and foldable PVC film as mask materials for facile microscale hydrophilic non-planar surface modification to establish a useful tool for PDMS prototyping and cell patterning.Human articular chondrocytes (hACs) are scarce and lose their chondrogenic potential during monolayer passaging, impeding their…[Read more]

Aluminum gallium arsenide has highly desirable properties for integrated parametric optical interactions large material nonlinearities, maturely established nanoscopic structuring through epitaxial growth and lithography, and a large bandgap for broadband low-loss operation. However, its full potential for record-strength nonlinear interactions is…[Read more]

The gut microbiota plays a pivotal role in the conversion of dietary flavonoids, which can affect their bioavailability and bioactivity and thereby their health-promoting properties. The ability of flavonoids to metabolically-activate the microbiota has, however, not been systematically evaluated. In the present study, we used a fluorescence-based…[Read more]

Aim of the study To evaluate changes in the elasticity of the coracohumeral ligament in patients with adhesive capsulitis of the shoulder treated with ultrasound-guided rotator interval injections. Methods Shear wave elastography was used to evaluate elasticity of the coracohumeral ligament in symptomatic and asymptomatic shoulders in the…[Read more]

This study indicated the association between free visual scanning and various cognitive functions in schizophrenia, shedding light on the possibility that some eye movement measures during visual exploration could be a biomarker for cognitive deficits in schizophrenia.

The rates and intensity of tobacco use are higher in persons with…[Read more]

Alginate based gels are widely adopted in many pharmaceutical and biomedical fields. The main rheological characteristics of the alginate-based gels are important design parameters for gel preparation. A new methodology for rheological tests on the alginate-based gels has been assessed in order to obtain reliable and reproducible results in terms…[Read more]

The LC3II/LC3I ratio and Atg5 level were upregulated by cGAS overexpression. Under calcification-inducing conditions, HDAC1 deacetylates cGAS and inactivates it. HDAC1 knockdown by short hairpin HDAC1 reversed the cGAS-induced reduction in vascular calcification, as well as in autophagy.

HDAC1-induced cGAS deacetylation enhances vascular…[Read more]

These data suggest a dual-therapy approach targeting both biofilm and planktonic populations can be further developed as a safe and efficient treatment of biofilm-mediated chronic S. Typhi infections.Clostridioides difficile is the major worldwide cause of antibiotic-associated gastrointestinal infection. A pathogenicity locus (PaLoc) encoding one…[Read more]