The assumption that during cortical embryogenesis neurons and synaptic connections are selected to form an ensemble maximising synchronous oscillation explains mesoscopic cortical development, and a mechanism for cortical information processing is implied by consistency with the Free Energy Principle and Dynamic Logic. A heteroclinic network…[Read more]

Conclusion Our study demonstrates the alterations of the abundance and diversity of the intestinal microbiota and the perturbation of metabolites in ZDF rats (fa/fa). We found three potential biomarkers of intestinal microbiota that may lead to perturbation in plasma metabolites. This may prompt new pathogenesis of obesity-related T2DM, but we…[Read more]

Engineered plant cell lines have the potential to achieve enhanced metabolite production rates, providing a high-yielding source of compounds of interest. Improving the production of taxanes, pharmacologically valuable secondary metabolites of Taxus spp., is hindered by an incomplete knowledge of the taxane biosynthetic pathway. Of the five…[Read more]

Herein, a thin film nanocomposite (TFN) membrane was prepared through deposition of a very thin mixed matrix layer of PEBAX®1657/chitosan-wrapped multiwalled carbon nanotubes (CWNTs) on an ultraporous polyethersulfone (PES) substrate. The eco-friendly CWNTs were synthesized via non-covalent functionalization of MWNTs by carbohydrate polymer…[Read more]

Introduction Accessory mitral valve tissue is a rare congenital disease of the mitral valve. It is usually associated with other cardiac malformations and/or left ventricular outflow tract obstruction. More than 2/3 of patients were diagnosed in their childhood. Treatment can be conservative or surgical. The suitable timing for surgery remains…[Read more]

4%, 31.6% and 37.6% respectively. Additionally, the capacitance values were 98, 126 and 168 F/g in the two-electrode system respectively, and their energy densities reached 3.35, 4.69 and 6.36 Wh/kg at a power density of 25 W/kg accordingly. The present work was aimed to develop the tissue benign, modified acid-functionalized single-walled carbon…[Read more]

Given the potential role for a reduction in PGC-1α expression or activity in Huntington Disease (HD), we compared reductions in transcripts found in the neocortex and hippocampus of these mice to that of an HD knock-in model; few of these transcripts were reduced in this HD model. These data provide novel insight into the function of PGC-1α in g…[Read more]

OBJECTIVE Peripherally inserted central catheter (PICC) is being increasingly used in critical care settings. However, PICC is associated with various complications, particularly venous thrombosis. Our aim was to observe the effects of preventive application of low molecular weight heparin on venous thrombosis in a PICC model. METHODS All rabbits…[Read more]

An unplanned ICU admission was a stressful event for family members, who looked to clinicians for emotional support. Developing trust was challenging, as family members struggled to feel like integrated members of the medical team when patients transitioned from one setting to another. Interpretation Family of patients experiencing an unplanned…[Read more]

ay. Copyright © 2020 Yue Geng et al.Acacia polyacantha is a medicinal plant traditionally used to treat livestock diseases and gastrointestinal infections; our study was undertaken to evaluate the antistaphylococcal activities of the methanolic leaf, bark, and root extracts, fractions, and compounds from Acacia polyacantha against a panel of 14…[Read more]