Colorectal cancer (CRC) is one of the most common cancers and a significant cause of tumor-related death worldwide. Traditional biomarkers, such as CEA and CA199, are not sensitive enough to provide useful information for early diagnosis and treatment and are rather used to track clinical progression of disease. There is growing evidence that…[Read more]

This finding contributes to the understanding of the complex and multilayered regulation of ADAM17 at the cell surface. Studies of habenula (Hb) function and structure provided evidence of its involvement in psychiatric disorders, including schizophrenia and bipolar disorder. Previous studies using magnetic resonance imaging (manual/semiautomated…[Read more]

BACKGROUND China’s limited health care resources cannot meet the needs of chronic disease treatment and management of its rapid growing ageing population. The improvement and maintenance of patient’s self-management is essential to disease management. check details Given disease management mainly occurs in the context of family, this study…[Read more]

AIM To validate the prognostic role of a panel of genes previously uncovered by our group to be specific targets of miRNAs differentially expressed in lung carcinoids with aggressive pathological features. METHODS Four genes, namely CREBP1, ACVR2B, LHX2 and KFL12, were identified in a previous study by our group using in silico analysis to be…[Read more]