89% vs 2.21%), families Coriobacteriaceae (Collinsella, T2D versus Healthy 2.62 % vs 1.25%) and Bifidobacteriaceae were enriched in elderly individuals with T2D, while members of Clostridiaceae (Clostridium, Healthy versus T2D 5.6% vs 3.2%) and Peptostreptococcaceae (Healthy versus T2D 3.45% vs 1.99%) were enriched in healthy volunteers. Pathways involved in amino acid biosynthesis were enriched in elderly individuals with T2D, while pathways involved in respiration and the biosynthesis of vital building blocks were enriched in healthy volunteers. Conclusions The study demonstrated for the first time in an African elderly population that the abundance of Bifidobacteriaceae, Collinsella, and Ruminococcus within the gut varies in relation to T2D. Findings from this study suggest that the restoration of features associated with healthiness via the way of gut microbiota modification could be one step needed to improve elderly patient care.Objective To understand the microbial species, antimicrobial sensitivity and drug resistance of patients in the nursing hospital, to bring clinical guiding significance to the use of antimicrobial in the nursing hospital. Methods A retrospective analysis of bacterial and drug sensitivity report of 2652 patients in nursing hospitals. Results There were 2652 cases of bacterial and drug sensitivity results, including 1202 positive cases, 652 females accounted for 54.24%, and 550 males accounted for 45.76%, concentrated in 70-99 years old. There were 57 kinds of bacteria, 303 cases of Gram-positive bacteria accounted for 25.21%, 808 cases of Gram-negative bacteria accounted for 67.22%, and fungi accounted for 7.57%. The positive samples were mainly from urine (35.94%) and sputum (48.59%). The main Gram-positive bacteria in the positive samples were Staphylococcus aureus (53.14%), Enterococcus faecalis (12.87%), Staphylococcus epidermidis (10.23%), Staphylococcus haemolyticus (6.93%), Enterococcus faecium (3.96%).sensitivity rate of tigecycline is 100%. The resistance rate of Candida glabrata to fluorocytosine is above 60%, the sensitivity rate to amphotericin B, fluconazole and itraconazole are above 60%, and the sensitivity rate of voriconazole is above 90%. Conclusion There is a difference between this data and the bacteria data in Shanghai. It is necessary to understand the bacteria sensitivity rate and resistance rate of antimicrobial in the nursing hospital, and it has certain guiding significance for the clinical of the nursing hospital.In the present study, results from the examination of mammalian teeth from the cave of Kalamakia with modern techniques, as well as a qualitative overview of the microvertebrate and lithic material, are presented together with a revision of previous related work done for the site, in order to assess the palaeoenvironmental conditions in the area and the role they played in the Neanderthal’s repeated occupation of the cave. Geometric morphometrics analyses performed on the first lower molars of Microtus spp. individuals revealed persistent populations of the subgenus Terricola, in which the presence of Microtus thomasi and Microtus subterraneus are continuous through the stratigraphic units. Mesowear analyses performed on ruminant teeth showed no significant variation in toothwear through time, except for relatively elevated levels of dietary abrasion for the more recent samples. The study of the lithics revealed that Neanderthals visited the cave in alternating short and more permanent episodes of occupation, with the human occupants exhibiting special concern for raw material economy, while exploiting poor raw materials for the construction of their tools. The overview of the microvertebrate remains showed a growing trend towards the upper stratigraphic units, where taxa typical of temperate climate, open woodland and shrubland become more dominant. These results, along with observations derived from previous studies, suggest that temperate climate and open environment were the factors that mainly contributed to making the cave of Kalamakia attractive as a habitation site to the humans of the area.Background The phenomenon where ambulant patients suffer sudden falls during the process of getting off the couch and walking to the changing room post magnetic resonance imaging (MRI) examination is uncommon. However, it can be a very disturbing experience for such patients. Therefore, there is the need to effectively support patients to avoid falls when they are getting off the MRI couch when the examination is completed. Methods Two ambulant patients who had undergone MRI were observed to have lost their balance when they attempted to get off from the MRI couch after their procedures. Face-to-face interrogations were made about what they felt. Results The two patients complained of experiencing some form of dizziness/vertigo when they got off the MRI couch. Conclusion This paper reported two cases of falls that occurred in an MRI facility. The aim was to emphasize the need for extra care and support for all patients who undergo MRI examinations due to the potential risk of MRI induced vertigo or dizziness regardless of the patient’s condition.Southwestern Japan suffered its worst rains in 2018 causing floods and mudslides, claiming 225 lives and forcing millions for evacuations. Referred as “Heisei san-jū-nenshichi-gatsugōu”, the disaster was the result of incessant precipitation caused by the interaction of typhoon “Prapiroon” with the seasonal rain front “Baiu”. The present epidemiological study aims to investigate disaster-induced health issues in 728 residents of Innoshima island in the Hiroshima Prefecture by comparing their clinical data in pre-disaster (2017) and disaster-hit (2018) years which was obtained from annual health screening. Comparison of data showed a significant increase in the urine protein concentration in victims following the disaster. Probing further into the household conditions, showed that a total of 59,844 households were affected with water outage during the heavy rains, which was accompanied by severe damage of sewerage pipelines with complete recovery process taking two weeks. ASP2215 This two weeks of the crisis forced victims to refrain from using restrooms which in turn led to infrequent urination, thereby explaining the increased urine protein concentration in victims following the disaster.