A 57-year-old male presented to the emergency department with right upper quadrant pain and constitutional symptoms. Initial investigation revealed biliary sepsis with features of chronic cholecystitis, multiple liver abscesses and a fistulous connection between the gallbladder and colon. He was subsequently diagnosed with a cholecysto-colonic…[Read more]

With a qualitative approach drawing from four focus groups, this study explored what aspects of preschool are valued most by 30 low-income Latino/a immigrant parents with children enrolled in a state-funded preschool program in Texas. Beyond the push and pull factors of necessity, convenience, and supply, parents reported valuing the…[Read more]

To evaluate the evolution of chemosensation via extended psychophysical testing in patients who suffered from sudden chemosensory loss due to coronavirus disease 2019 (COVID-19). Additionally, this study sought to determine whether odor threshold testing provided additional information on olfactory loss due to COVID-19 compared to the more common…[Read more]

Across clerkships there is a need for better use of evidence based pedagogies to support emotional development.

There is an educational need for developmental space for students during General Practice, greater focus on preparing students for relationship building during Paediatrics and addressing stigma and personal safety issues in students…[Read more]

The transition from a breast cancer patient to a survivor can be associated with significant physical, psychological, and social challenges. Development of multidisciplinary evidence-based care during the post-treatment period is a key area of cancer research. This study examined survivorship issues, unmet needs and perceptions about care among a…[Read more]

ions, especially in oncology. As a turbo spin-echo based technique, it can be applied in most challenging regions where SS-EPI is problematic.Patterns of low frequency brain-wide activity have drawn attention across multiple disciplines in neuroscience. Brain-wide activity patterns are often described through correlations, which capture concurrent…[Read more]

Findings from animal models suggest that exercise increases all molecular aspects of the Nrf2-ARE pathway in all tissues studied. It was noted that there seems to be an age-related decline in Nrf2 protein upregulation with exercise training. In humans, however, there is a lack of evidence to support this claim.

Human induced pluripotent stem…[Read more]

After adjusting the models by age, sex, and Tanner stage, we found a significant association between the polymorphism and markers of adiposity. For each extra copy of the risk allele, we found an increase of 2.47 kg body weight (95% CI 1.39-3.55); 1.06 kg/m2 BMI (95% CI 0.56-1.54); 2.55 cm WC, (95% CI 1.26-3.85); and 1.98% body fat (95% CI…[Read more]

Tessitura-the habitual pitch range of a musical piece or role-is widely accepted as a significant factor in determining whether a singer should perform a given piece or role. However, attempts to quantify tessitura have historically relied on laborious hand calculations. The current study introduces a novel MATLAB program (“Tessa”) that automates…[Read more]

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Indirect treatment comparison showed no statistically significantdifferences in reduction of ≥ 50% migraine days/month betweenerenumab, fremanezumab and eptinezumab. Probable clinical equivalencewas found between these drugs in terms of efficacy and safety,therefore they could be considered equivalent therapeutic alternatives i…[Read more]