The results indicated that the plasma concentration and the systemic exposure of tizoxanide (T) after oral administration of O-carbamoyl tizoxanide prodrugs were much greater than that produced by equimolar dosage of nitazoxanide. It was also found that the plasma concentration and the systemic exposure of tizoxanide glucuronide (TG) were much…[Read more]

We found that constructs from the HPM are empirically improved dietary behavior among the women population. This result provides a suitable source for designing strategies of a nutrition education intervention for improving the frequency and nutrient intake of breakfast consumption among female students.Hypopharyngeal perforation (HP) is a…[Read more]

Therefore, we identify the interplay of mitochondrial hyperacetylation and inflammation as a key driver in HFpEF pathogenesis, which can be ameliorated by promoting β-hydroxybutyrate abundance.

Therefore, we identify the interplay of mitochondrial hyperacetylation and inflammation as a key driver in HFpEF pathogenesis, which can be ameliorated…[Read more]

rather than older, age at diabetes diagnosis was associated with higher risk of mortality and vascular disease. Early and sustained interventions to delay type 2 diabetes onset and improve blood glucose levels and cardiovascular risk profiles of those already diagnosed are essential to reduce morbidity and mortality. Graphical abstract.

The…[Read more]

Job satisfaction and life satisfaction are important determinants of the mental health of business professionals.

Business professionals are important to the economic welfare of their organization and of society as a whole. Our study suggests that demographic characteristics, work-related aspects and subjective dimensions of well-being…[Read more]

The absence of E. hellem and E. cuniculi infection suggests a low risk of zoonotic foodborne transmission from these wild lagomorph species in southern Spain. To the authors’ knowledge, this is the first report of E. intestinalis infection in wild rabbits and Iberian hares. The presence of E. bieneusi and E. intestinalis in organ meats from wild…[Read more]