Furthermore, a variety of long- and short-lived gamma-emitting radionuclides were detected in the rainwater samples collected on April 7, 2011. Among them, short-lived radionuclides such as 140La, 110mAg, 95Nb, 125Sb, 113Sn, 129Te, 129mTe, 132Te, 132I, and 136Cs, were observed. The findings of this study provide evidence for the direct effects of FNPPA-derived radionuclides in Jeju Island. This is the first location in Korea and the first in the entire East Asian region, excluding Japan that is confirmed to have been directly affected FNPP accident.Staphylococcus aureus infection is common in the clinical environment. It has been shown that the presence of micro/nano structures on material surfaces promote bacterial adhesion resistance. Herein, we assessed the S. aureus adhesion properties on laser micro/nano structured stainless-steel (316 L) surfaces after mechanical rotation and ultrasonic washing. The interaction force between S. aureus and structured surfaces was evaluated. A high concentration S. aureus solution was used to evaluate the bacterial sterilization efficiency after film formation on the stainless-steel surface. After 24 h of incubation, S. aureus films were formed on material surfaces. The comparison of static washing, surface mechanical rotation, and ultrasonic washing showed a decrease of S. aureus adhesion on the polished and laser induced periodic surface structures. However, S. aureus adhesion on the micro/nanoparticle surface after mechanical rotation washing did not display any obvious change compared to the polished one. Additionally, specimens after ultrasonic cleaning showed clear antibacterial adhesion than mechanical rotation. After the ultrasonic sterilization process, the laser induced periodic laser surface sample showed optimal bacterial adhesion inhibition. Finally, in vitro tests showed that the biocompatibility of the laser-induced structured surface did not change significantly from the polished surface one.The purpose of this study is to design and evaluate a new tubular assembly structure of Hexakis (m-phenylene ethynylene) (m-PE) macrocycles and to explore its potential application as an innovative drug delivery system. First, we focused on how (m-PE) macrocycles can be self-assembled in both chloroform (CHCl3) and water solvents for the formation of the assembled nanotube using molecular dynamics (MD) simulations. In contrast to their behavior in water solvent, all ten (m-PE) macrocycles remain aggregated at low concentrations of CHCl3. We found that these macrocycles carrying chiral side chains and capable of H-bonded self-association, assemble into tubular stacks. Then, the dual delivery strategy for the transport of doxorubicin (DOX) and curcumin (Cur) on the self-assembly system of hexakis (m-PE) nanocarrier is examined using molecular dynamics (MD) simulation and free energy calculation. The obtained results indicated that the binding energy of DOX (- 298.9 kJ/mol) on hexakis (m-PE) in the presence of Cur is higher than free DOX (- 247.7 kJ/mol). Furthermore, in the interaction of the DOX and hexakis m-PE, the contribution of van der Walls (vdW) energy is higher than electrostatic (elec) energy, which can be related to the strong π-π interactions between the drug molecules with the carrier surface. KU-57788 cell line In general, the results indicated that the simultaneous delivery of DOX and Cur through DOX/Cur/hexakis (m-PE) could be a promising vehicle in tumor therapy. Based on the obtained results of the present research, hexakis (m-PE) macrocycle can be used as a drug delivery vehicle for targeted or systemic delivery.

Benign tumors of the esophagus are rare. However, among them, leiomyomas are common. Tumors larger than 5 cm are rare and may present as dysphagia or epigastric pain. Combined esophagoscopy and video-assisted thoracoscopic surgery or laparoscopic trans hiatal resection are used the management of leiomyoma of esophagus.

This case report illustrates the case of a young male who presented with dysphagia and occasional dyspnea. Imageology demonstrated an esophageal mass which on surgical exploration and histopathology, confirmed the diagnosis of leiomyoma.

Esophageal leiomyomas vary in their presenting size from a few centimeters to greater than 5 cm which are rare. The preferred surgical technique for leiomyomas is transthoracic enucleation without opening the mucosa, which is easier, faster, and safer compared to resection. In our patient, due to the size and location of the tumor, it was resected using an abdominal approach, and a distal esophagectomy and esophagogastrostomy were performed.

A multi-modal approach involving both the endoscopic and radiologic examinations is crucial in ensuring that the morbidity of malignancy is avoided.

A multi-modal approach involving both the endoscopic and radiologic examinations is crucial in ensuring that the morbidity of malignancy is avoided.

Some cardiac surgical patients present low cardiac output syndrome due to ventricular dysfunction resulting from postischemic myocardial stunning. We present a case of using unusually high dose of inotropes so that we could avoid mechanical circulatory support after cardiac surgery.

A 65-year-old man underwent elective cardiac surgery. His immediate cardiac output was poor and vital signs were unstable. We aggressively increased the dose of catecholamine above usual dose and the cardiac output was elevated. The patient recovered without significant myocardial injury. After a few years, TTE showed more improved left ventricular function compared with preoperative state.

In a stunned myocardium, response to catecholamine is thought to be dull. Thus, if adequate response to usual dose of catecholamine is not achieved in a post cardiac surgical patient, we think that there may be a room for more increment of inotropes.

Unusually high dose of catecholamine may be helpful in a patient with severe ventricular dysfunction associated with stunned myocardium.

Unusually high dose of catecholamine may be helpful in a patient with severe ventricular dysfunction associated with stunned myocardium.

Thyroid papillary carcinoma rarely present as manubriosternum metastasis. The standard treatment for patients with metastatic disease is iodine ablation therapy. A surgical resection is a good option for patients with resectable limited bony metastasis.

We report a case of a 50-year-old female with thyroid gland enlargement. Positron emission tomography scan (PET) showed a solitary manubriosternal metastasis. The patient underwent total thyroidectomy and claviculo-manubriosternal en-bloc resection and improvised reconstruction using Methyl methacrylate marlex mesh plate (MMS). Post-operative recovery was uneventful, and the patient received adjuvant radioactive iodine (RAI) treatment. At five year follow up patient remained disease-free.

In conclusion, we report a case of papillary carcinoma of thyroid with solitary manubriosternal metastasis treated with total thyroidectomy and radical en-bloc resection of clavicular heads, manubriosternal and reconstruction by our modified reconstruction technique, which provides the best MMS plate stability, cosmoses, and good disease-free survival.