BACKGROUND AND OBJECTIVES The elderly patient is particularly vulnerable to potentially inappropriate prescription (PIP) due to physiological reasons, comorbidity, polypharmacy or the different pharmacokinetics/pharmacodynamics of drugs. The aim of this study was to determine the prevalence of PIP according to the STOPP-START criteria in patients…[Read more]

We found that LHX2, BMP-5 and GDF11 had complex interactions with other missing proteins and BMP-5 had both tumor suppressing and tumorigenic roles. BMP-5 may be involved in fibrosis and tumorigenic processes in the liver. These results provide us an understanding of the mechanism of HBx-induced disorders, and may serve as molecular targets for…[Read more]

38 per person in medical costs, discounted at 3%.The aim was to analyze the extent to which anthropometric values, in line with body image and physical ability, predict physical self-concept, and the latter, in turn, predicts the practice and intention to pursue physical activity. A total of 302 participants, 150 males and 152 females were…[Read more]

esistance to a threshold level at which natural selection can be expected to take over.Background Congenital generalized lipodystrophy (CGL) is a rare disorder characterized by the lack of adipose tissue and metabolic complications with predominantly autosomal recessive inheritance. There are 6 different genes known to cause CGL with 4 main types…[Read more]