The enthalpies for the Pt substitution reactions, i.e., Pt + OAnOn+ → PtAnOn+ + O, are calculated to range from about 14-62 kcal/mol, and the Pt-AnOn+ bond dissociation enthalpies range from about 78-149 kcal/mol for the ground electronic states. For the PtAnO+ species, the LSSs were all predicted to be the ground state, whereas the PtAnO2+ m…[Read more]

In addition, the prognostic value of intensified PRO collection throughout therapy on survival and disease progression is promising. Future perspectives in the field of PROs and MBC are described.We report a study of carbon dots produced via bottom-up and top-down routes, carried out through a multi-technique approach based on steady-state…[Read more]

SpaCE is a consensus-based certification standard that seeks to improve health outcomes and more integrated care.

Incidental discovery of pancreatic cystic neoplasms (PCLs) is a common and steadily increasing occurrence. The aim of this study was to investigate a cohort of patients presenting with incidentally detected PCLs which were not…[Read more]

Mutation A405D, which introduces a negatively charged residue into an intrinsic disordered region (IDR) of hJPH2, turns liquid-like droplets into amyloid-like aggregates. Depletion of an Alanine Rich Region in the IDR recapitulates the liquid-amyloid phase transition. The MORN repeat regions of hJPH2 encodes intrinsic tendency to form amyloid-like…[Read more]