Bifunctional or amphoteric photoacids simultaneously present donor (acidic) and acceptor (basic) properties making them useful tools to analyze proton transfer reactions. In protic solvents, the proton exchange between the acid and the base is controlled by the acidity or basicity strength and typically occurs on two different pathways known as…[Read more]

ObjectiveTo explore the gender difference of clinical features in patients with obstructive sleep apnea hypopnea syndrome （OSAHS）, and explore the relationship between OSAHS and gender. Methods4499 patients with OSAHS were examined by polysomnography （PSG） and Epworth sleepiness scale （ESS）. Subjects were divided into mild, moderate and severe…[Read more]

Pancreatic ductal adenocarcinoma is one of the common malignant tumors of the digestive tract. It has the characteristics of strong occlusion, aggressiveness, easy metastasis, and resistance to radiotherapy and chemotherapy. Therefore, its five-year survival rate is extremely low, with a rate of less than 8%. Looking for a new treatment is an…[Read more]

g., C4d, C3a, C3d,g, sC5b-9, TAT, and D-dimer. Strong associations were found between the blood cascade systems and organ damage, illness severity scores, and survival. We show that critically ill COVID-19 patients display a conjunct activation of the IIIS that is linked to organ damage of the lung, heart, kidneys, and death. We present evidence…[Read more]

Idiopathic spontaneous intraperitoneal hemorrhage (ISIH) is a rare but potentially fatal entity. The majority of the reported cases of ISIH due to middle colic artery rupture are associated with pseudoaneurysm. Our case is unique in that no pathology could be identified. To our knowledge, this is the third case report in the literature of a…[Read more]

Oligomycin was used to induce HEI-OC1 cell damage in vitro. In HEI-OC1 cells treated with oligomycin, 8-CPT and ESI-09 increased and reduced cell apoptosis, respectively. Moreover, 8-CPT promoted Ca2+ uptake in HEI-OC1 cells, while ESI-09 inhibited this process. In conclusion, our data provide strong evidence that the Epac1 signaling pathway…[Read more]

Results IR regularization strength influenced CAC scores significantly ( p less then 0.05 ). The CAC volumes and scores between FBP and IRs were the most similar when the IR regularization strength was chosen to match the MTF of the FBP reconstruction. Conclusion When the regularization strength is selected to produce comparable spatial resolution…[Read more]