The newly identified features correlated well with specific biomarkers traditionally used in clinical practice (r up to 0.73), and outperformed them in correlating with visual acuity ([Formula see text] compared to [Formula see text] for conventional markers), despite representing an enormous compression of OCT imaging data (67 million voxels to…[Read more]

g children’s hospitalization affects the level of agreement between reports on their HRQOL.An amendment to this paper has been published and can be accessed via the original article.

Melnick-Needles syndrome (MNS) is an extremely rare osteochondrodysplasia caused by a mutation of FLNA, the gene encoding filamin A. MNS is inherited in an…[Read more]

It is concluded that natural convection heat transfer in a cochlea during robotic cochlear implant surgery can be neglected. It is found that thermal trauma is avoided by applying a power density from 2.265 × 107 W/m3 for 114 s to 6.6×107 W/m3 for 9 s resulting in a maximum temperature increase of 6°C on the magnet boundary.In popular accounts, st…[Read more]

The average YIAT score was 33.16 ± 15.68. Overall 18%, 59.9%, 46.8% of students scored above validated cutoff scores for internet addiction, poor sleep quality and depression respectively. Prevalence of IA among males and females were 20.4% and 12.9% respectively. Significant correlations were found between potential IA, sleep quality and depr…[Read more]

alculated and relatively cheap.

To describe the mid-term outcome after inferior selective crossectomy in a subset of patients with symptomatic chronic venous disease and both great saphenous vein and suprasaphenic valve incompetence.

Retrospective analysis of prospectively collected data was conducted. During an eight-year period, 1095…[Read more]

Nanofiltration (NF) is an advanced environmental technology in water treatment. To thin film nanocomposite (TFN) membrane, good compatibility between nanofillers and polyamide (PA) layer is the guarantee of remarkable performance. Herein, tannic acid (TA) was employed as modifier of UIO-66-NH2 prior to the interfacial polymerization (IP). With TA…[Read more]

In children with postprocedural AIS, time to diagnosis was delayed. Most patients presented multiple potentially modifiable RFs as hemodynamic alterations and infections.Stem cell-based regenerative therapies may rescue the central nervous system following ischemic stroke. Mesenchymal stem cells exhibit promising regenerative capacity in in vitro…[Read more]

In this review, we will discuss the recent advances, advantages and disadvantages of different CRB1 human and animal retinal degeneration models. In addition, we will describe novel therapeutic tools that have been developed, which could potentially be used for retinal gene augmentation therapy for RP patients with variations in the CRB1…[Read more]

The coronavirus disease 2019 (COVID-19) pandemic poses a current world-wide public health threat. read more However, little is known about its hallmarks compared to other infectious diseases. Here, we report the single-cell transcriptional landscape of longitudinally collected peripheral blood mononuclear cells (PBMCs) in both COVID-19- and…[Read more]

Glucose modification may improve the oral bioavailability of drugs or achieve targeted drug delivery.

The membrane transport mechanism of some glycoside drugs may be related to glucose transporters. Glucose modification may improve the oral bioavailability of drugs or achieve targeted drug delivery.Andrographolide, the main bioactive component…[Read more]

Maternal mortality is unacceptably high in our region. In 2015, the Latin American Center for Perinatology and Women´s Reproductive Health (CLAP) created a regional network of institutions including 16 countries, committed to improving epidemiological surveillance and healthcare of women in a situation of abortion or near miss event, using a…[Read more]