BACKGROUND Periampullary cancers (PAC) including pancreatic, ampulla of Vater (AOV), and common bile duct (CBD) cancers are highly aggressive with a lack of useful prognostic markers beyond T stage. However, T staging can be biased due to the anatomic complexity of this region. Recently, several markers related to cancer stem cells and…[Read more]

hormone therapy is a medically necessary treatment for many transgender individuals with gender dysphoria, not all transgender patients experience gender dysphoria and not everyone desires hormone treatment. Gender-affirming hormone therapy is not effective contraception. Sexually active individuals with retained gonads who do not wish to become…[Read more]

tion, while the global epigenetic modification is dependent on the genetic background. Our research suggests an innovative insight in explaining the reason behind the occurrence of transgenic plants with random and undesirable phenotypes.Mitochondrial dynamics is essential for the maintenance of cell homeostasis. Previous studies have shown that…[Read more]

PURPOSE Due to differences in attenuation and the Electron Return Effect (ERE), the presence of gas can increase the risk of toxicity in Organs At risk (OAR) during Magnetic Resonance guided Radiotherapy (MRgRT). Current adaptive MRgRT workflows using density overrides negate gas from the dose calculation, meaning that the effects of ERE around…[Read more]

Globally, the designed perturbations generated activity in different muscles with different magnitudes (P-values≤0.05). Increased spinal stiffness was observed at each spinal level during the hip extension, and at L5 during the held inhalation (P-values<0.05). A differential effect of the spinal levels on the spinal stiffness was observed during t…[Read more]

This work is expected to pave a new and practical pathway for physiological monitoring during sleep. Myricetin This review aimed to analyse the current state of management practices for poultry manure in Poland and present future perspectives in terms of technologies allowing closing the loops for circular economy, and thus recovery of nutrients…[Read more]

There is a strong association between socioeconomic status and surgical outcomes; however, the optimal method for socioeconomic risk-stratification remains elusive. We aimed to compare 2 metrics of socioeconomic ranking by ZIP code, the Distressed Communities Index, and the Area Deprivation Index and their association with surgical…[Read more]

LNM, which could help to develop individualized treatment strategies in clinical practice.

MRI radiomic model based on anatomical and functional MRI images could be used as a non-invasive biomarker to identify PTC patients at high risk of LNM, which could help to develop individualized treatment strategies in clinical practice.

The aim of…[Read more]

Members of the genus Sneathia are fastidious bacteria that predominantly colonise the female genital tract and are significantly associated with reproductive disorders and genital and neonatal disease. From a taxonomical perspective, the genus only comprises the species Sneathia sanguinegens. Numerous reports on a second species, ‘Sneathia amnii’,…[Read more]

In birds, the female is heterogametic (ZW) and the male homogametic (ZZ). The small W chromosome comprises only 28 protein coding genes (homologues to Z chromosome counterparts) and a number of repeat regions. Here, we report our analysis of one of these genes, BTF3 (basic transcription factor 3), which exhibits differential expression during…[Read more]