After acquired brain injury (ABI), patients show various neurological impairments and outcome is difficult to predict. Identifying biomarkers of recovery could provide prognostic information about a patient’s neural potential for recovery and improve our understanding of neural reorganization. In healthy subjects, sleep slow wave activity (SWA,…[Read more]

ther emphasizes the role of preemptive analgesia in mitigating postoperative sternotomy pain and it’s role as a plausible safe analgesic adjunct facilitating fast tracking with sternotomies on systemic heparinization.

PIB is safe for presternotomy administration and provided significant quality of pain relief postoperatively, as seen after…[Read more]

The Warburg observation concerning ATP generation in cancer cells is analyzed with regard to the likely involvement of H+ resonance effects on the angular velocity of the ATP synthase rotor. It is reasonable to expect that the variety of diseases associated with mitochondrial dysfunction may in part be related to the ATP synthase rate of rotation.…[Read more]

1% vs 27.3%; odds ratio [OR], 1.34; 95% CI, 1.28-1.39; P  less then  0.001). Multivariable logistic regression analyses showed that vulnerable groups of the quarantined population included those with pre-existing mental disorders or chronic physical diseases, frontline workers, those in the most severely affected areas during outbreak, inf…[Read more]

4% in their 60s, and 14.1% aged ≥ 70 years. The primary reason for switching to the NRTI-sparing regimen was due to reduced renal function. According to the limited data, viral suppression was achieved at week 48 in all patients in the NRTI-sparing group. No patient had treatment failure nor developed drug resistance. The use of NRTI-sparing r…[Read more]

3%) vaginal and 30 (48.4%) laparoscopic. The algorithm sorted only 25 of the 62 abdominal cases (40.3%) to the abdominal approach. Conclusion Use of a hysterectomy route selection algorithm preoperatively improves identification of candidates for minimally invasive hysterectomy.Background Systemic lupus erythematosus (SLE) is an autoimmune disease…[Read more]

these clinical trials through improvements in their design and delivery. Their use will help to efficiently identify the safest and most effective AI interventions and commission them with confidence for the benefit of patients and the public.

The SPIRIT-AI and CONSORT-AI guidelines provide the first international standards for clinical trials…[Read more]

Additionally, it is tempting to speculate that GAL may be used in the treatment of gastroenteritis. This review aims to present the function of GAL in the mammalian gastrointestinal tract under physiological conditions. In addition, since GAL is undoubtedly involved in the regulation of inflammatory processes, and the aim of this publication is to…[Read more]

Our study provided a potential explanation to the controversial prognostic indication of PKM, and could invoke future studies focusing on revealing the biological and oncological roles of these alternative spliced variants of PKM.

Postoperative pain after video-assisted thoracoscopic surgery (VATS) affects patients’ recovery, postoperative…[Read more]

Our study provided a potential explanation to the controversial prognostic indication of PKM, and could invoke future studies focusing on revealing the biological and oncological roles of these alternative spliced variants of PKM.

Postoperative pain after video-assisted thoracoscopic surgery (VATS) affects patients’ recovery, postoperative…[Read more]

The benefits of physical activity for the physical health of individuals are well documented. Less is known about the benefits of physical activity for mental health. This paper explores the associations between physical activity and positive mental health and mental health problems. The paper utilises data collected from a representative sample…[Read more]