Over 6 months, the change in HRV was similar between subjects treated with empagliflozin vs. placebo for the following parameters RMSSD -1.2ms (-6.0 to 3.6ms); pNN50 0.5% (-2.6 to 3.6%); VLF -907.8ms

(-2388.8 to 573.1ms

); LF -341ms

(-878.7 to 196.7ms

); HF -33.8ms

(-111.1 to 43.5ms

); LFHF -0.1 (-0.4 to 0.2). Subjects who…[Read more]

S. for other indications, 197 (20%) are licensed outside the U.S. or are in human trials, and 595 (61%) are pre-clinical investigational compounds.

CoV-RDB facilitates comparisons between different candidate antiviral compounds, thereby helping scientists, clinical investigators, public health officials, and funding agencies prioritize the…[Read more]

The modeling of the diffusion MRI signal from moving and deforming organs such as the heart is challenging due to significant motion and deformation of the imaged medium during the signal acquisition. Recently, a mathematical formulation of the Bloch-Torrey equation, describing the complex transverse magnetization due to diffusion-encoding…[Read more]

Finally, we investigated the ability of bacteria to inhibit the chalkbrood fungus Ascosphaera apis. Mass spectroscopy analysis revealed that the bee gut isolates Frigoribacterium sp. PF-04965842 and Bacillus senegalensis produce gluconic acid. We further found that this simple sugar is involved in chalkbrood fungal hyphal lysis and cytoplasmic…[Read more]