We use the effect of OPRM1 genetics on opioid response to illustrate how these analyses could be conducted and conclude by discussing how PGx-PD could be translated into clinical practice to improve therapeutic outcomes.

There are minimal data on long-term surgical outcomes of patients who have undergone resection for Wilms tumor (WT) and…[Read more]

Clinicians and researchers are invited to always refer to the latest update of each classification.

Different versions of the TNM classification can be confounding for the scientific community. Citing the 8th edition of the UICC TNM Classification of Malignant Tumours or the AJCC Cancer Staging Manual without specifying the precise version used…[Read more]

By contrast, genes containing candidate missense mutations in the lowland breeds are related to cell cycle (

), cell adhesion (

), and coat color (

).

We found new variants in genes with potentially functional consequences to the adaptation of local sheep to their environments in Wales. Knowledge of these variations is…[Read more]