Introduction Vitamin B12 deficiency is widely prevalent across many low- and middle-income countries, especially where the diet is low in animal sources. While many observational studies show associations between B12 deficiency in pregnancy and infant cognitive function (including memory, language and motor skills), evidence from clinical trials…[Read more]

Human activity is drastically altering the habitat use of natural populations. This has been documented as a driver of phenotypic divergence in a number of wild animal populations. Here, we show that urban and rural populations of red foxes (Vulpes vulpes) from London and surrounding boroughs are divergent in skull traits. These changes are…[Read more]

Elastic and viscous association of lamin-B1 and lamin-A is supported by transcriptional and proteomic profiling analyses. Chromatin decondensation quantified by electron microscopy softens the nucleus unless lamin-A is expressed. A mechanical framework is provided for assessing nucleus response to applied forces in health and disease. © 2020 The…[Read more]

Sirtuin 2 (SIRT2) belongs to the sirtuins family. It exists in many tissues and organs of the human body and regulates a wide range of biological functions. Studies have found that the abnormal expression of SIRT2 was associated with a variety of malignant tumors. SIRT2 possesses an important role in tumorigenesis, with both tumor-promoting and…[Read more]

The prediction accuracy of GS and phenotypes was similar to each other regardless of the amount (0, 50, 100%) of stage-1 data incorporated in the GS model. Ranking of stage-1 lines by GS predictions that used no stage-1 phenotypic data had marginally lower correspondence to stage-2 phenotypic rankings than rankings of stage-1 lines based on…[Read more]

The PVDF membrane with a thin film coating containing 3 wt% of PVA and 1 wt% of TiO2 showed high photocatalytic degradation for the three dyes studied under UV irradiation due to uniform dispersion of TiO2 nanoparticles over the membrane surface. Further, smaller the molecular weight of the dye, larger the photodegradation that was observed.The…[Read more]

Among the genes deleted in NTV, C7L or/and K1L gene was mainly responsible for its replication defect. Protein C7 interacted with SAMD9, which antagonized the antiviral response of SAMD9 to ensure viral protein translation and replication of NTV in non-permissive cell lines. Our finding will serve as a baseline for modification of NTV in future…[Read more]

For the three kinds of accidents, the functional effect in the monthly trend of the accidents was signification (P= less then 0.001). Conclusion The rates for all three kinds of accidents decreased. The increase in accident rates from the beginning of 2014 to Mar 2016 maybe due to the generalization of insurances in Iran and the increase in the…[Read more]

17; 95% CI 0.08-0.26; P less then .01). CONCLUSIONS The resistin/uric acid index can be considered a prognostic factor for identifying adolescents with overweight or obesity with a greater probability of improving their BMI. This index could help establish different interventions for adolescents with overweight and obesity; however, additional…[Read more]

In the present study anatomical characterization of 20 medicinally important Asteroideae species were done under light and scanning electron microscopy. Variety of qualitative and quantitative anatomical characters like epidermal cells, stomata, guard cells, subsidiary cells, trichomes and oil droplets were observed. Generally pentagonal,…[Read more]

19.2%, P  less then  0.01). CONCLUSION In this cohort of bicycle injuries in the ED of a level 2 trauma center, e-bikers were older and had more comorbidities than CB users. Except for a higher rate of thoracic and soft-tissue trauma in e-bikers, no differences were found in the mechanism and severity of injury. While it is important to note tha…[Read more]