350, 5.327, p = 0.001) predicted autism severity. Auranofin chemical structure CONCLUSIONS AND IMPLICATIONS Children with ASD in this study had a high level of autism severity. Regular anthropometric measurements by healthcare professionals should be conducted at the autism intervention centres. It is important to have multidisciplinary col…[Read more]

Basal ganglia regions are part of the brain’s reward-processing networks and are implicated in the neurobiology of obesity and eating disorders. This study examines basal ganglia microstructural properties in adults with and without obesity.

Diffusion basis spectrum imaging (DBSI) images were analyzed to obtain putative imaging markers of…[Read more]

A new intramolecular oxidative amino-hydroxylation of o-allenyl anilines is reported. Treatment of carbamate-protected anilines with lead(IV) carboxylates in dichloromethane at room temperature results in facile tandem C-N (allene cyclization) and C-O bond formation (carboxylate trapping) to form indole products. Detailed reaction scope,…[Read more]

Thereby, we identified the Set1/MLL methyltransferase complex member RBBP-5 as a novel germ cell reprogramming barrier. Our findings demonstrate that CONJUDOR increases efficiency and versatility of RNAi screens to examine interconnected biological processes in C. elegans with high-throughput.Gene duplication is a major mechanism to create new…[Read more]