The binding affinities of 1 and 3 were stronger than those of 2 and 4 possibly because of the difference in the substituent groups of these molecules. These flavones could also decrease membrane leakage and upregulate cell viability by reducing the formation of toxic oligomers. Moreover, the performance of these flavones in terms of binding…[Read more]

Suppression of PFTK1 significantly inhibited the cell migration and invasion in H1299 and 95C cells. Notably, after PFTK1 downregulation, the epithelial-mesenchymal transition (EMT) markers vimentin, ZEB1 and β-catenin were obviously decreased. Additionally, immunofluorescence analysis indicated that PFTK1 downregulation remarkably induced…[Read more]

53×10-5cm2/W (divergent Gaussian beam). In addition, the corresponding third-order nonlinear optical susceptibility of the sample was also estimated as ∼1.43×10-5esu and ∼1.75×10-5esu, respectively. The experimental results imply a novel potential application of ferrofluid in nonlinear phase modulation devices.High-power nanosecond laser pulses…[Read more]