The characteristics of physician communication with patients at the end of life (EOL) in East Asia have not been well studied. We investigated physicians’ communications with imminently dying patients with cancer and their families in palliative care units (PCUs) in Japan, South Korea, and Taiwan.

This observational study included patients with cancer newly admitted and deceased during their first admission to 39 PCUs in three countries. We evaluated 1) the prevalence and timing of informing patients and families of patients’ impending death and 2) the prevalence of communication to assure the families of the patient’s comfort.

We analyzed 2138 patients (Japan 1633, South Korea 256, Taiwan 249). Fewer Japanese (4.8% 95% confidence interval [95% CI], 3.8%-5.9%) and South Korean (19.6% 95% CI, 15.2%-25.0%) patients were informed of their impending death, whereas 66.4% (95% CI, 60.2%-72.1%) of Taiwanese were informed; among all three countries, ≥90% of families were informed. Although most patients in all e differences and the effects of such communications in East Asia.

Sickle cell disease (SCD) is associated with recurrent pain that could lead to abnormal sensory patterns (ASPs).

The purpose of this study is to compare children with SCD who had normal sensory patterns (NSPs) and ASPs in pain experience, physical function, pain coping, and pain catastrophizing.

Children with quantitative sensory testing data were selected from a larger study that examined pain and symptoms in children with SCD. Comparisons were made between children with NSP (n=35; 13.9±1.9years) and ASP (n=13; 12.8±1.9years). Children completed the Adolescent Pediatric Pain Tool, Functional Disability Inventory, Pain Coping Questionnaire, and Pain Catastrophizing Scale.

No significant differences were found in pain intensity (2.9±3.0 vs. 2.6±2.8 on 0-10 Visual Analogue Scale) between the NSP and ASP, respectively. The most common marked pain sites for both groups were lower extremities (22.9%), head and neck (20.8%), and upper extremities (20.8%). Functional Disability Inventory scores were significantly worse in ASP (38.5%) compared with NSP (11.4%). The ASP group had significantly worse scores in emotion-focused pain coping subscales.

Children with SCD with ASP had worse functional disability, were expressing more affective pain quality, and had emotion-focused pain coping compared with NSP. Future studies are needed to examine the effectiveness of physical activities on the physical function as well as psychosocial interventions such as peer support and creative arts expression to minimize development of ASP in children with SCD.

Children with SCD with ASP had worse functional disability, were expressing more affective pain quality, and had emotion-focused pain coping compared with NSP. Future studies are needed to examine the effectiveness of physical activities on the physical function as well as psychosocial interventions such as peer support and creative arts expression to minimize development of ASP in children with SCD.

In palliative care, caregivers often lack words and competences to discuss patients’ needs in social and spiritual dimensions. The Utrecht Symptom Diary-4 Dimensional (USD-4D) is an instrument that can be used to monitor symptoms and needs in the physical, psychological, social, and spiritual dimensions and to optimize communication between patients and caregivers.

To assess the content validity of the USD-4D items related to the social and spiritual dimensions from a patient’s perspective, measured in terms of comprehensibility, relevance, and comprehensiveness.

An explorative qualitative study was conducted using in-depth semistructured interviews and thematic analysis. SB203580 clinical trial Twelve participants (male N=7, 53-87years old) with an estimated life expectancy of less than oneyear were recruited in two home care services a general hospital and a hospice.

The instructions, items, and response options were comprehensible for almost all participants. The meaning that was provided to the items was expressed in themes maintaining personal identity and autonomy, resilience, letting go, perceived balance in one’s life, and death and afterlife. This corresponds with the intended meaning. The items were relevant at some points in time. Not all participants had needs for personal care during the interviews. Participants found the USD-4D comprehensive, no key concepts related to the social or spiritual dimensions appeared to be missing.

The USD-4D constitutes a content valid PROM from the patient’s perspective. The items support patients in identifying needs in the social and spiritual dimensions and in the conversation to further explore these needs.

The USD-4D constitutes a content valid PROM from the patient’s perspective. The items support patients in identifying needs in the social and spiritual dimensions and in the conversation to further explore these needs.

Many advanced patients with cancer have unrealistic prognostic expectations.

We tested whether offering life expectancy (LE) statistics within palliative chemotherapy (PC) education promotes realistic expectations.

In this multicenter trial, patients with advanced colorectal and pancreatic cancers initiating first or second line PC were randomized to usual care versus a PC educational tool with optional LE information. Surveys at twoweeks and threemonths assessed patients’ review of the LE module and their reactions; at threemonths, patients estimated their LE and reported occurrence of prognosis and end-of-life (EOL) discussions. Wilcoxon tests and proportional odds models evaluated between-arm differences in LE self-estimates, and how realistic those estimates were (based on cancer type and line of treatment).

From 2015 to 2017, 92 patients were randomized to the intervention and 94 to usual care. At baseline most patients (80.9%) wanted “a lot” or “as much information as possible” about the impact of chemotherapy on LE. Among patients randomized to the intervention, 52.0% reviewed the LE module by twoweeks and 66.7% by threemonths-of whom 88.2% reported the information was important, 31.4% reported it was upsetting, and 3.9% regretted reviewing it. Overall, patients’ LE self-estimates were very optimistic; 71.4% of patients with colorectal cancer estimated greater than five years; 50% pancreatic patients estimated greater than two years. The intervention had no effect on the length or realism of patients’ LE self-estimates, or on the occurrence of prognostic or EOL discussions.

Offering LE information within a PC educational intervention had no effect on patients’ prognostic expectations.

Offering LE information within a PC educational intervention had no effect on patients’ prognostic expectations.