21±0.42 kg, and the rate increase of serum ferritin was higher in combination NE+MNB and biscuit group (2.54 μg/L and 2,17 μg/L). At the end of study there were a significant decrease in prevalence of underweight (p=0.003), the incidence of underweight in NE+MNB (45.2%) lower than NE group (63.3%), MNB group (64.5%) and control group (69,0%) and significant decrease of iron deficiency (p=0.02), the incidence lower in MNB group (6.5%) than NE+MNB (22.6%), NE group (23.3%) and control group (24.1%). The combination of nutritional education and multi-nutrient biscuits intervention improving nutritional and iron deficiency status on undernourished children. These risearch highlight the need integration of nutrition education and food base intervention to prevent underweight and iron deficiency on children 6-23 mo old.Anemia is a condition in which the number of red blood cells or hemoglobin levels in the blood is less than normal. Anemia remains a major problem for global public health. The World Health Organization (WHO) estimates that anemia affected more than 1.62 billion people worldwide. Data from National Health Survey (Riskesdas) in 2013 shown that anemia prevalence was 21.7%. Yogyakarta Health Profile showed that the prevalence of anemia women of reproductive age has increased from 22,45% to 28,1% between 2010 and 2014, while in Bantul was 20% indicating a moderate public health problem. The objective of this study was to determine the correlation between knowledge, iron intake, and folate intake with anemia status among women of reproductive age in Bantul Regency. This research used cross sectional method. The samples were selected by using probability sampling method with simple random sampling technique by lottery and specifying inclusion and exclusion criteria. Data was analyzed with Chi-square test using SPSS. The results showed that there was no correlation between knowledge level and anemia status. Anemia status was significantly correlated with iron intake, but not with folate intake. Conclusion Anemia was associated with iron intake among women of reproductive age.Anemia is one of the major problems among female adolescents in Indonesia. Weekly iron-folic acid supplementation was a cost-effective measure to tackle adolescent anemia. However, adherence to the supplementation is low. This study was aimed to explore the determinants of t highschool females’ adherence to consume iron-folic acid tablets. Using cross sectional design with 274 subjects. After obtaining consent the data were collected, coded and analysed using SPSS23. The inclusion criteria were high school female from 18 schools which had iron tablets program. The majority of subjects was 14-16 y old (73.7%). The majority of schools gave iron tablets to students without organizing taking iron tablets together (63.5%). The adherence to consume iron and folic acid tablets in this study was 45.6% (n=125). Almost half of highschool female (36.1%) cited they did not think that iron tablets are necessary while 12.4% cited experiencing side effects. Factors that were correlated (p less then 0.005) were school organizing taking iron tablets together, the student’s age, knowledge, motivation, self efficacy, prior Hb level examination, and teacher educating the benefits of iron tablets to students (OR=9.5, CI=5.4-16.8, OR=0.43, CI=0.23-0.78, OR=2.12, CI=1.29-3.48, OR=6.55, CI=3.77-11.4, OR=6.39, CI=3.7-10.9 respectively). The most important factors which determined highschool female’s adherence were school organizing students to take iron tablets together at school (OR=7.2, CI=3.5-14.6, p=0.000), student’s motivation (OR=5.3, CI=2.5-11.3, p=0.000), and class teacher educating students on anemia and IFA (OR=2.3, CI=1.2-4.6) meanwhile student’s knowledge, self efficacy, and prior Hb level examinations were confounding factor.Vitamin B12 is a water soluble micronutrient found in animal foods. Its deficiency is not uncommon in India owing to vegetarianism but often unrecognized due to diverse clinical manifestations. read more This review aims to collate the current data on vitamin B12 status in healthy Indian adult and elderly population. Online database Pubmed was searched for articles published in English between 2000 and 2019. Inclusion criteria consisted of original studies conducted on apparently healthy adult and elderly Indian population reporting serum/plasma vitamin B12 levels. Comprehensive literature search identified 14 studies eligible for inclusion. The deficiency prevalence reached 78.5% and 61.7% among adults and elderly, respectively, based on varying cut offs. Higher vitamin B12 levels were reported in women than men. Hyperhomocysteinemia (Hcy >15 μmol/L) was lower in females as compared to males (60% vs 90%, 14.9% vs 57.4% and 3.6% vs 20.9% respectively in three studies). Vitamin B12 deficiency was higher in vegetarians. The results indicate that inadequate vitamin B12 status is a wide spread problem in the Indian population. However, variety of laboratory methods and cut-offs of vitamin B12 deficiency and the heterogeneity in results pose challenges to draw clear conclusions on the extent of vitamin B12 deficiency in India. This review, therefore, highlights the need for more evidence based research to define age and sex specific cut offs for defining vitamin B12 deficiency.This study aims to analyze the effect of Bilih fish bars (BFB) on oxidative stress based on the levels of MDA and SOD in diabetic rat models. This study used a Randomized Complete Design (RCD). Forty white male rats of the Sprague-Dawley strain were placed into the following five groups normal and diabetic rats that were fed either the standard feed and metformin, BFB, BFB, and metformin or BFF with a zinc dose of 0.54 mg. A single dose of STZ (40 mg/kg) was used to induce diabetes in the rats. The intervention lasted for 30 d. The differences in MDA and SOD levels between groups were determined with one-way ANOVA followed by Duncan’s New Multiple Range Test, and the significance of the statistical level was set at p0.05). BFB and BFF lowered blood sugar levels and decreased the oxidative stress levels based on MDA levels in a diabetic rat model.