Late grade 2 and grade 3 genitourinary and gastrointestinal toxicity rates were 9 and 0.3%, and 0.3, and 0%, respectively. CONCLUSIONS The present protocol of carbon ion radiotherapy for prostate cancer provided low genitourinary and gastrointestinal toxicity with good biochemical control within 5 years. TRIAL REGISTRATION University Medical I…[Read more]

367 ± 0.066 mm vs 2.369 ± 0.062 mm [SD], P = .815. The corrected distance visual acuity was 6/6 at 1 month in 80% of the participants in the UltraSert group and 86% in the Vivinex group. After adjusting for age, sex, grade of cataract, and IOL power, no significant difference was found in the magnitude of surgically induced astigmatism (SIA) in t…[Read more]

nd provide an immunological perspective for individualized therapies.

Andrographolide (Andro), a diterpenoid extracted from

, has been shown to attenuate pulmonary fibrosis in rodents; however, the potential mechanisms remain largely unclear. This study investigated whether and how Andro alleviates bleomycin (BLM)-induced NOD-like…[Read more]

Besides, the surface characteristics of AC and Fe/AC before and after PS oxidation were evaluated by XPS and SEM. A quenching test used MeOH as an inhibitor and EPR spectra of free radicals were conducted to develop the proposed reaction mechanisms for PFOA oxidation. The sources of microplastics and other anthropogenic particles in freshwater are…[Read more]

Patients with localized relapse had better survival including PFS 2 (P=0.023), PRS (P=0.004), and overall survival (OS) (P=0.029). Patients who achieved complete resection tended to have longer PFS 2 (P=0.017). After multivariate analysis, complete resection at recurrence remained as an independent positive predictor for PFS 2 (P=0.022). The…[Read more]

An expedient one-pot synthesis of carbocyclic spiro[5.5]undeca-1,4-dien-3-ones via 1,6-conjugate addition initiated formal [4+2] annulation sequences by employing p-quinone methides and sulfonyl allenols is presented. Furthermore, this synthetic protocol tolerates a wide variety of p-quinone methides and sulfonyl allenols and affords the…[Read more]

vascular disease prior to invasive hemodynamic testing. © The Author(s) 2020.Background Acute right heart failure (RHF) is the main cause of death in patients with acute pulmonary embolism and emergent pulmonary hypertension. However, the molecular mechanisms underpinning the acute RHF and the interactions between the right (RV) and left…[Read more]

Based on the measured tritium contents, a map of the spatial distribution of tritium in the room was created. The results were used to calculate the radiation dose for a person working in the room and showed no significant contribution to the approved average annual dose for workers. A committee classifier was developed for use in the application…[Read more]

Here we investigated effects of intramuscular (i.m.) heating-needle stimulation on persistent muscle nociception evoked by i.m. injection of different doses (50-200 µl) of complete Freund’s adjuvant (CFA) in rats. Paw withdrawal reflexes evoked by noxious mechanical and heat stimulation as well as hind limb swelling were determined prior to and tw…[Read more]

In this paper,the name,origin,producing area,harvesting and processing changes of Paeonia lactiflora used in classical prescriptions were studied by textual research of herbal medicine and field investigation. Chinese herbaceous peony wasn’ t distinguished before the Northern and Southern Dynasties; Tao Hongjing proposed that there were two kinds…[Read more]