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McKenzie Cormier posted an update 12 hours, 31 minutes ago
A 10μg/m
increase in PM
in the two-day moving average corresponded to a 0.72% (95% CI 0.02-1.42%) incremental increase in hemorrhagic stroke, and a 10μg/m
increase in PM
in the four-day moving average corresponded to a 0.14% (95% CI 0.06-0.22%) incremental increase in ischemic stroke.
High particulate matter might be a risk factor for stroke among patients with T2D. PM
and PM
have a linear exposure-response relationship with stroke among T2D patients. The study provided evidence of the risk of stroke due to particulate matter pollution among patients with comorbid T2D.
High particulate matter might be a risk factor for stroke among patients with T2D. PM2.5 and PM10 have a linear exposure-response relationship with stroke among T2D patients. The study provided evidence of the risk of stroke due to particulate matter pollution among patients with comorbid T2D.
It is established that the severity of depressive and anxiety symptoms is associated with poorer quality of life (QOL) in persons with drug-resistant epilepsy. We aimed to verify the presence of subsyndromic depressive episodes (SDEs) and subsyndromic anxiety episodes (SAEs) in persons with temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) compared to healthy controls and to determine the impact of depressive and anxiety symptoms on patients’ QOL.
We prospectively evaluated 35 persons with TLE-HS and 90 healthy controls. QOL was assessed by the Epilepsy Surgery Inventory (ESI) and QOL in Epilepsy Inventory-31 (QOLIE-31). The Beck Depression Inventory (BDI) and the State-Trait Anxiety Inventory (STAI-X) were used to assess symptoms, and SDEs and SAEs diagnosis were made considering the total scores of BDI (<9) and STAI-Trait (<49), respectively.
Persons with TLE-HS had higher symptoms on BDI, STAI-S, and STAI-T. They have 3.011 greater odds of presenting SDEs and 7.056 times odds, SAEs. The depressive and anxiety symptoms, added in the model with epilepsy-related factors, accounted for a significant increase in the variance in several aspects of QOL. Anxiety-trait symptoms are the most critical individual determinant of the QOL.
Our results demonstrated that persons with TLE-HS had greater odds of presenting SDE and SAE than healthy controls. Besides, there was a relationship between anxiety and depressive symptoms and worse QOL in TLE-HS. It is essential to be aware of psychiatric symptoms, even though these symptoms do not meet the criteria to be considered a “disorder.”
Our results demonstrated that persons with TLE-HS had greater odds of presenting SDE and SAE than healthy controls. Besides, there was a relationship between anxiety and depressive symptoms and worse QOL in TLE-HS. It is essential to be aware of psychiatric symptoms, even though these symptoms do not meet the criteria to be considered a “disorder.”The present study explored rape acknowledgment among 131 college women survivors of rape utilizing three subgroups acknowledged rape, unacknowledged rape, and ambivalent acknowledgment. Posttraumatic stress disorder (PTSD) symptom clusters and parameters of victimization and were compared between the subgroups. Crenolanib Of the participants, 28.2 % were classified as ambivalent rape acknowledgment, 49.6 % as acknowledged rape, and 22.1 % as unacknowledged rape. Across all four PTSD symptom clusters, the ambivalent acknowledgment group had significantly higher PTSD symptoms than the unacknowledged group. With the exception of hyperarousal symptoms, PTSD symptoms did not differ between the acknowledged and ambivalent acknowledgment groups. With regard to potential group differences in exposure to various rape tactics (i.e., physical force, threat, incapacitation), the acknowledged group indicated (a) exposure to a greater number of rape tactics relative to the other groups, (b) higher likelihood of endorsing rape via threat than the ambivalent acknowledgment group, and (c) more frequent endorsement of forcible rape than the unacknowledged group. Results are discussed in light of screening methods to assess for PTSD symptoms among rape survivors, as well as the recent changes to the Title IX law regarding sexual misconduct reports on college campuses.
We aimed to evaluate the association between baseline plasma zinc and the development of proteinuria as well as possible effect modifiers in hypertensive patients.
This is a subset of the China Stroke Primary Prevention Trial (CSPPT) Renal Sub-Study. In the CSPPT, participants were randomized to receive a daily oral dose of 1 tablet containing 10 mg enalapril and 0.8 mg folic acid or 1 tablet containing 10 mg enalapril only. A total of 783 participants with plasma zinc measurements and without proteinuria at baseline were included in the current study. The study outcome was the development of proteinuria during the follow-up, defined as a urine dipstick reading of trace or ≥1+ at the exit visit.
During a median follow-up duration of 4.4 years, the development of proteinuria occurred in 93 (11.9 %) participants. There was an inverse relation of baseline plasma zinc with the development of proteinuria (per SD increment; OR, 0.74, 95 % CI 0.55-0.99), p for trend of quartiles = 0.005.
In Chinese hypertensive patients, there was a significant inverse association between baseline plasma zinc and the development of proteinuria, although plasma zinc remained in the reference range.
In Chinese hypertensive patients, there was a significant inverse association between baseline plasma zinc and the development of proteinuria, although plasma zinc remained in the reference range.Rates of natural source zone depletion (NSZD) are increasingly being used to aid remedial decision making and light non-aqueous phase liquid (LNAPL) longevity estimates at petroleum release sites. Current NSZD estimate methods, based on analyses of carbon dioxide (CO2) and oxygen (O2) soil-gas concentration gradients (“gradient method”) assume linear concentration profiles with depth. This assumption can underestimate the concentration gradients especially above LNAPL sources that are typically characterized by curvilinear or semi-curvilinear O2 and CO2 concentration profiles. In this work, we proposed a new method that relies on calculating the O2 and CO2 concentration gradient using a first-order reaction model. The method requires an estimate of the diffusive reaction length that can be easily derived from soil-gas concentration data. A simple step-by-step guide for applying the new method is provided. Nomographs were also developed to facilitate method application. Application of the nomographs using field data from published literature showed that NSZD rates could be underestimated by nearly an order of magnitude if reactivity in the vadose zone is not accounted for.