The aim of this study was to reveal the biodegradation characteristics and physiological response mechanism of a newly isolated bacterium to 2,4,6-trinitrotoluene (TNT) contamination. A Klebsiella variicola strain with high efficiency of TNT degradation was used as the test strain to analyze the changes in cell growth, morphology, and functional…[Read more]

or French patient cohorts, we observed a good correlation of POSPOM with in-hospital mortality. Therefore, further adjustments of POSPOM considering also multicentre and transnational validation should be pursued based on this proof of concept.

Very old patients (≥ 80 years-old, VOP) are increasingly admitted to intensive care units (ICUs). C…[Read more]

A 49- year old immunocompetent male presented with a right flank abscess and was found to have disseminated cryptococcal disease. Treatment was initiated with a one-week intravenous regime of amphotericin B and flucytosine based on recent trial data that this is as effective, and less toxic, than the standard two weeks. After completion of…[Read more]

An exploratory whole-brain analysis revealed widespread activation differentially associated with performance of the mnemonic discrimination task. Taken together, these results suggest that a network of brain regions contribute to mnemonic discrimination performance, with the hippocampus and parahippocampal cortex as a hub in the network…[Read more]