Pathological hyperphosphorylated tau is a key feature of Alzheimer’s disease (AD) and Frontotemporal dementia (FTD). Using transgenic mice overexpressing human non-mutated tau (htau mice), we assessed the contribution of tau to peripheral and central neurodegeneration. Indices of peripheral small and large fiber neuropathy and learning and memory…[Read more]

5% vs. 3.0%; p < 0.001), and had higher viral load in respiratory samples (9,404,000 [586,060-10,000,000] vs 1560 [312-25,160] copies/mL; p = 0.002).

Even if based on a small sample population, this proof-of-concept study poses the basis for an early identification of patients at higher risk of SARS-CoV-2 viremia, and therefore likely…[Read more]

The survival was 100% at 14 days, and 90% at 30 days and at 4 years. One patient died as a result of multiorgan failure on day 16 of intensive care unit stay. The mean mitral valve gradient across the percutaneous valve was 2.26±1.047 mmHg, and the mean valve area was 2.20±0.14 cm2. Through the 4 years follow up, the New York Heart Association c…[Read more]

To evaluate the efficacy and safety of drug-eluting bead-transcatheter arterial chemoembolization (DEB-TACE) using 100-300 μm versus 300-500 μm CalliSpheres microspheres (CSMs) for treating multiple hepatocellular carcinoma (HCC) with the largest nodule measuring between 5 and 10 cm.

Eighty-one advanced-stage HCC patients treated by D…[Read more]

Meanwhile, CD8+was not significantly associated with TST (p=0.118).

It is necessary to check the expression of mRNA gene Treg, Treg, CD4

, and CD8

with more samples to find the mean value that shows the protective value of further TB.

It is necessary to check the expression of mRNA gene Treg, Treg, CD4+, and CD8+ with more…[Read more]

In conclusion, risk communication and community engagement are an essential and challenging aspects of the containment of the COVID-19 outbreak and thus we have to try our best to establish a better system to ensure that risk communication is well in place and utilized effectively to engage the community.

Viral hemorrhagic fevers (VHF) refers…[Read more]