DOCA-hypertensive mice also exhibited an increase in the vascular oxidative fluorescence intensities, the protein expressions of gp91phox and p22phox, and the fibrotic factors transforming growth factor β and fibronectin. TNFα deficiency reduced oxidative stress and fibrotic protein expressions. The DOCA mice also showed a decrease in the p…[Read more]

treatment options.Hepatocellular carcinoma (HCC) represents the most commonly diagnosed liver cancer worldwide, and the overall survival of patients with unresectable disease is poor. In the last five years, immune checkpoint inhibitors (ICIs) have revolutionized the treatment scenario of several hematological and solid tumors, and these agents…[Read more]

38, 0.55; Ptrend less then 0.001) for vitamin B2, 0.55 (95%CI 0.46, 0.76; Ptrend less then 0.001) for vitamin B6 and 0.72 (95%CI 0.60, 0.86; Ptrend less then 0.001) for vitamin B12, respectively. No statistically significant association was found between methionine intake and colorectal cancer risk. Stratified analysis by sex showed that the…[Read more]

03 to 0.06 μm, p = 0.044) and internal spherical aberration (from -0.10 to -0.05 μm, p = 0.049) after atropine use. Differences in corneal spherical aberration were insignificant.

The positive shift of spherical aberration induced by the inhibition of accommodation in myopic children may have a possible effect against myopic progression. F…[Read more]