Male and female condoms are the only available Multipurpose Prevention Technologies (MPTs) that can prevent unintended pregnancy and sexually transmitted infections including HIV. If used correctly and consistently, condoms can provide levels of pregnancy protection similar to many hormonal methods. Condoms remain one of the most common methods…[Read more]

BACKGROUND Chemical exposure leading to ototoxicity is a fresh challenge for occupational healthcare in South Africa. OBJECTIVES The critical question is ‘what is known about occupational ototoxic chemicals with or without noise exposure in South Africa?’ METHOD This qualitative, mapping study was completed with published (peer-reviewed) and grey…[Read more]

All four precancerous cell lines were highly sensitive to Wee1 inhibition by Adavosertib (AZD1775), while primary keratinocytes tolerated this inhibitor. Wee1 inhibition caused induction of DNA damage during S-phase followed by mitotic failure in (pre)cancer cells. In conclusion, we uncovered Wee1 inhibition as a promising chemopreventive strategy…[Read more]

The objective of this paper is to apply high-speed photography and schlieren method to investigate the bubble dynamics between the free surface and a rigid wall. The temporal evolution of the bubble shape and the free surface motion are recorded by two synchronous high-speed cameras. Experiments are carried out for a single bubble generated at…[Read more]

The objective of this paper is to apply high-speed photography and schlieren method to investigate the bubble dynamics between the free surface and a rigid wall. The temporal evolution of the bubble shape and the free surface motion are recorded by two synchronous high-speed cameras. Experiments are carried out for a single bubble generated at…[Read more]

05).

There was no significant increase in hemolysis among the groups, which demonstrates that the VAVD technique, even if lower negative pressure is preferred, can be applied safely and effectively to improve venous drainage and consequently, cardiac decompression, even if smaller venous cannulas are used, and also avoid from superfluous…[Read more]

In terms of BCVA at month 6, ranibizumab was superior to laser treatment, with an advantage of 0.14 logMAR, 95% CI 0.01 to 0.25, p = 0.030. The positive effect of ranibizumab disappeared after treatment was discontinued. Similar results without statistically significant difference were found with respect to macular thickness. In both groups, no…[Read more]

3% (5 of 95) in the normal macula group, 16.4% (23 of 140) in the CME group, and 66.2% (47 of 71) in CNV group. The difference between automated and manual macular thickness was higher than 10% in 1.4% (2 of 140) in the CME group and in 28.17% (20 of 71) in the CNV group. Only one case in the normal group had a higher than 10% segmentation error…[Read more]