These data show an EV-mediated spreading of pro-inflammatory response between mast cells, and provide the first in vivo evidence for the biological role of mast cell-derived EVs.Microglia, the immunocompetent cells of the central nervous system (CNS), play an important role in maintaining cellular homeostasis in the CNS. These cells secrete…[Read more]

To examine the outpatient opioid prescribing practices and the factors associated with opioid prescriptions in patients with Rheumatoid Arthritis (RA).

This cross-sectional study used the 2011-2016 National Ambulatory Medical Care Survey. Descriptive weighted analyses were used to examine the trends in opioid prescribing practices for RA.…[Read more]

For N, more needs to be done. Some sub-basins need to reduce their pollution more than others. Equality considerations call for reducing both point (e.g. Selleckchem Ac-DEVD-CHO recycling manure resources on the land) and diffuse (improve nutrient use efficiencies in agriculture) sources of N in the rivers. Our study is the first to link a Gini…[Read more]

To compare the role of spectral-domain optical coherence tomography (SD-OCT) in regard to retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) assessment in the detection of primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG) progression.

In the prospective study, 131 subjects with PACG and POAG were…[Read more]