Immunotherapy has become a hotspot in cancer therapy in recent years. Several immune checkpoints inhibitors have been used to treat lung cancer. CD137 is a kind of costimulatory molecule that mediates T cell activation, which regulates the activity of immune cells in a variety of physiological and pathological processes. Targeting CD137 or its…[Read more]

In this study pillar[5]arene (P5) and a quinoline-functionalized pillar[5]arene (P5-6Q) which is used for detecting radioactive element, gas adsorption and toxic ions were synthesized. These materials were characterized by Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared (FTIR), elemental analysis, melting point, Mass Spectroscopy,…[Read more]

The weaknesses are related to unprepared CHAs and the inefficient qualifications to serve this population. The barriers to seeking comprehensive care are particularly physical, economic, geographical, and infrastructural. Final Considerations It is imperative to give visibility to people with disabilities in the rural context, considering the…[Read more]