psychiatry, there is no protocol describing the application of telemedicine in adolescent medicine and psychiatry. There is an urgent need for further evaluation of the use of telemedicine for this population. This kind of research will improve knowledge about the effectiveness, acceptability and limitations of using a teleconsultation device in…[Read more]

The understanding of the mechanisms linking these cellular characteristics to the accelerated aging and to the wide spectrum of affected tissues and clinical symptoms in the MDPL patients may provide opportunities to develop therapeutic treatments for progeroid syndromes.We previously determined that different vitamin D metabolites can have…[Read more]

hiCTR1900025495. Registered 29 August 2019.

Metabolic Syndrome (MS) is a construct relating to a series of metabolic dysfunctions attributable to insulin resistance and obesity. Here, we estimate the incidence of MS according to their individual components using a Mexican open-population cohort.

We evaluated data of 6144 Mexicans…[Read more]

Without herd immunity, routine infant vaccination had the lowest incremental cost-effectiveness ratio estimates.

Routine MenB vaccination does not offer substantial value for money, mainly due to high vaccine costs and low disease incidence.

Routine MenB vaccination does not offer substantial value for money, mainly due to high vaccine…[Read more]

By using the Lyapunov stability theory, stability analysis of the proposed robust optimal integral sliding-mode control strategy is performed. Finally, the collaborative simulation platform based on the Carsim and MATLAB/Simulink is developed. The simulation results illustrate the advantage of the proposed robust optimal control strategy for the…[Read more]

D. Don (Apiaceae family) is a perennial plant whose oleo- gum resin is used as a natural remedy for various diseases, especially chronic bronchitis, and asthma. In the present study, hydromethanolic extract of

root was subjected to phytochemical analyses and α-glucosidase inhibitory potentials of the isolated compounds were assessed.…[Read more]

It was also noticed that the internalized PCL-R15/siRNA nanoplexes were transported through digestive routes and trapped in lysosomes, which may be the bottleneck for efficient siRNA delivery of PCL-R15/siRNA nanoplexes. This study investigated the relationship between the polymer structure of PCL-R15 and the cellular interaction patterns, which…[Read more]

There are multiple barriers, which influence these reporting practices. Improved reporting systems are needed to affect a change in the current environment.

There are low levels of formal AE reporting, especially amongst doctors, within Johannesburg Academic EM Departments despite large numbers of AEs experienced. There are multiple barriers,…[Read more]

general population.

The Ethics Committee for Research, University Putra Malaysia (13th March 2019). Reference UPM/TNCPI/RMC/1.4.18.2 ( JKEUPM ).

The Ethics Committee for Research, University Putra Malaysia (13th March 2019). Reference UPM/TNCPI/RMC/1.4.18.2 ( JKEUPM ).

As the incidence of secretory osteoporosis has increased, bone…[Read more]