SBDs in PAH and CTEPH (groups 1 and 4 of the clinical classification of PH, respectively), as well as therapeutic options, will also be discussed.

Given the vast number of cystic fibrosis transmembrane conductance regulator (

) mutations, biomarkers predicting benefit from CFTR modulator therapies are needed for subjects with cystic…[Read more]

Proteins with a metallo-beta-lactamase (MBL) fold have been largely studied in bacteria in the framework of resistance to beta-lactams, but their spectrum of activities is broader. We show here that the giant Tupanvirus also encodes a MBL fold-protein that has orthologs in other giant viruses, a deep phylogenetic root and is clustered with…[Read more]

While we only studied a small sample, the characterization may hold when larger samples are studied.

Human movement, rehabilitation, and allied sciences have embraced their ambitions within the cycle of “RehabMove” congresses over the past 30years. This combination of disciplines and collaborations in the Netherlands has tried to provide…[Read more]