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  • Sandoval Doherty posted an update 8 hours, 21 minutes ago

    Our results show that ptau levels of all analyzed residues and age groups are similar without strong increases over age. These data show that tau is already phosphorylated at the age of 3 months suggesting that phosphorylation starts even earlier. The early start of tau phosphorylation in htau mice enables the use of these mice for efficacy…[Read more]

  • Sandoval Doherty posted an update 1 day, 8 hours ago

    ne-sensitive lipase; IR insulin receptor; IRS insulin receptor substrate; JNK c-JUN N-terminal kinase; MGL monoacylglycerol lipase; NaF sodium fluoride; NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells; PBS phosphate buffered- saline; PCB pyruvate carboxylase; PDE phosphodiesterase; PKA protein kinase cAMP-dependent; PMSF…[Read more]

  • Sandoval Doherty posted an update 2 days, 8 hours ago

    The potential of pulsed electric field (PEF) of different intensities (8, 18, and 28 kV/cm) on the conformation and gelation properties of myofibrillar proteins (MPs) extracted from pale, soft, and exudative-like (PSE-like) chicken meat was investigated. The results showed a positive correlation between gelation properties and PEF intensities in t…[Read more]

  • Sandoval Doherty posted an update 2 days, 8 hours ago

    The potential of pulsed electric field (PEF) of different intensities (8, 18, and 28 kV/cm) on the conformation and gelation properties of myofibrillar proteins (MPs) extracted from pale, soft, and exudative-like (PSE-like) chicken meat was investigated. The results showed a positive correlation between gelation properties and PEF intensities in t…[Read more]

  • Sandoval Doherty posted an update 3 days, 7 hours ago

    confirm that cholesterol-enriched lipid microdomains, often called lipid rafts, are important in bacterial adhesion. These findings demonstrate that plasma membrane adhesion via bacterial flagella play a significant role for an important human pathogen. This mechanism represents a promising target for the development of novel antiadhesion…[Read more]

  • Sandoval Doherty became a registered member 3 days, 7 hours ago

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