This case ended up being unusual since the client did not manifest any classical features of Cushing’s syndrome at the time of presentation with bilateral CRVO, and only a couple of months later on had remarkable weight-loss, muscle tissue weakness and acute psychosis. He got intravenous etomidate and underwent emergency transsphenoidal…[Read more]

Furthermore, the activation of NLRP3 inflammasome was noted in major microglia addressed with CuCl2, followed by the increased levels of cleaved caspase-1, ASC, and interleukin-1β. Blocking NLRP3 inflammasome activation with siNlrp3 or MCC950 paid off interleukin-1β and interleukin-18 production, thereby effectively mitigating cognitive d…[Read more]