Carboxyl ester lipase (CEL) encodes a cholesterol ester hydrolase that is secreted into the duodenum as a component of pancreatic juice. The objective of this study was to characterize the CEL gene, investigate the association between the CEL promoter variants and chicken phenotypic traits, and explore the CEL gene regulatory mechanism. An…[Read more]

Histological analysis showed lower lipid accumulation in the DM/G-CSF group than in the DM/saline-treated rats. Protein levels of LC3 and beclin-1 were higher, and those of p62 were lower in the DM/G-CSF rats than in the DM/saline-treated rats. The mRNA expression of

-oxidation-related genes was higher in DM/G-CSF rats than in the…[Read more]

2, 20.9, 13.3, and 29.7 mL, respectively. The muscle volume of the men was greater than that of the women (all P  less then  0.001), and the fat infiltration ratio was positively correlated with body mass index (all P  less then  0.05). CONCLUSIONS The semi-automated quantified measurement of fatty infiltration of the rotator cuff muscles using…[Read more]

Further, we apply this method to analyze the data from a cardiovascular clinical trial as an illustration.High sucrose can induce tau hyperphosphorylation and cognitive dysfunction/memory impairment as observed in Alzheimer’s disease (AD). Rutaecarpine, a specific (transient receptor potential vanilloid 1 [TRPV1]) agonist, is neuroprotective…[Read more]

This study presented for the first time the development and validation of a sensitive method for quantification of dopamine, noradrenaline, and adrenaline in Krebs-Henseleit solution by LC-tandem mass spectrometry. Docetaxel in vitro Aliquots of 2.0 mL calibrators, quality controls, and samples of Krebs-Henseleit solution incubated with t…[Read more]