These are likely to uncover currently unknown mechanisms with implications for the prevention of craniofacial malformations. The zebrafish appears to be an excellent complementary model with high translational value to study these complex interactions.Autosomal dominant osteopetrosis type II (ADO II), characterized by increased bone mass and…[Read more]

Beside the known H

S pathways, additional, tissue-specific, enzymatic systems, involved in H

S production and elimination, might exist.

Mitochondria play a key role in the regulation of H2S and GSH metabolism pathways. However, further studies are needed to understand the consequences of abnormalities of H2S and GSH synthesis on the…[Read more]

05). Taken together, the results indicated that IL-17 promoted proliferation and inflammation and inhibited apoptosis of HaCaT cells by interacting with the TRAF3IP2 adaptor protein, while knockdown of the expression of TRAF3IP2 reduced the effects of IL-17 in HaCaT cells.Schwann cells are unique glial cells in the peripheral nervous system. These…[Read more]