Bariatric surgery may be indicated in patients with nonalcoholic fatty liver disease (NAFLD) to achieve and maintain the degree of weight loss required to ensure therapeutic effects. However, bariatric surgery is still underrecognized in the treatment of NAFLD, including its inflammatory subtype, nonalcoholic steatohepatitis (NASH). Moreover,…[Read more]

BEST PRACTICE ADVICE 1 For all procedures, especially procedures carrying an increased risk for perforation, a thorough discussion between the endoscopist and the patient (preferably together with the patient’s family) should include details of the procedural techniques and risks involved. BEST PRACTICE ADVICE 2 The area of perforation should be…[Read more]

Induced pluripotent stem cells generated from human peripheral blood T cells display stem cell morphology and pluripotency markers. Furthermore, RGC-like cells differentiated from TiPSC exhibit extending axons and RGC marker TUJ1. When transplanted intravitreally into NMDA-treated mice, embryo bodies derived from TiPSC survived, migrated, and…[Read more]

Furthermore, global-attention (GA) regularization is proposed to guide two attention streams to better model dynamics of composite features with the reference to the global information. Fusion at the softmax layer is adopted to make better use of the implicit complementary advantages between SA, LA, and GP streams and get the final comprehensive…[Read more]

The mineralization of increased organic matter can release CO2 and reduce pH in the vicinity, which can further result in the acidic dissolution of detrital apatite. In turn, most of the released phosphorus can be adsorbed or co-precipitated with calcium minerals, resulting in the significant increase of Ca-P. The mechanisms of phosphorus…[Read more]

ocapsid proteins were comparable in PCR-positive and PCR-negative cases.

The presence of IgG antibodies to nucleocapsid protein was associated with substantially reduced risk of reinfection in staff and residents for up to 10 months after primary infection.

UK Government Department of Health and Social Care.

UK Government…[Read more]

Healthcare stereotype threat was related to poorer mental and physical health among LGB individuals; this was true when these outcomes were assessed over the past 30 days but not when they were assessed in general. Cohort differences in healthcare stereotype threat suggest potential important within group variation that needs further…[Read more]

Furthermore, considering focal loss constraints for each pixel independently, we propose an alternative training fashion that trains the model with focal loss and dice loss alternatively. The segmentation model can not only benefit from the pixel-wise focal loss but also from the region-wise dice loss to comprehensively optimize the model. We…[Read more]

Various electrocardiographic (ECG) indices have been shown to be useful for early recognition and staging of cardiac involvement in Fabry Disease (FD). However, many of them lack acceptable sensitivity and specificity. We assessed the value of automated ECG measures to discriminate between pre-hypertrophic FD and healthy individuals.…[Read more]